Table 1

Weekly blood counts from the introduction of deferiprone until the agranulocytosis had developed.

Weeks after therapy start
0§1*23*45*6*78*9#
Hemoglobin (g/L) 109 81 93 73 91 70 84 105 83 87 
WBC (x109/L) 5.4 3.7 4.0 3.9 5.5 3.8 3.7 4.6 2.5 0.9 
ANC (x109/L) 3.7 2.4 2.7 2.6 4.0 2.6 no data 3.0 1.4 <0.1 
Platelets (x109/L) 273 234 227 263 222 170 278 208 151 164 
Ferritin (microgram/L)  2027   1740 1986 1716  1491  
Weeks after therapy start
0§1*23*45*6*78*9#
Hemoglobin (g/L) 109 81 93 73 91 70 84 105 83 87 
WBC (x109/L) 5.4 3.7 4.0 3.9 5.5 3.8 3.7 4.6 2.5 0.9 
ANC (x109/L) 3.7 2.4 2.7 2.6 4.0 2.6 no data 3.0 1.4 <0.1 
Platelets (x109/L) 273 234 227 263 222 170 278 208 151 164 
Ferritin (microgram/L)  2027   1740 1986 1716  1491  
§

Values prior to start of deferiprone therapy

*

Erythrocyte transfusions 15 ml/kg body weight

#

Deferiprone therapy was stopped this day and the patient was admitted to hospital the following day with septicemia

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