Table 4

Genes associated with clonal dominance preferentially belong to three GO categories: intracellular signaling, transcription factor, and apoptosis

ProcessIDDb, %SCDb, %IDDb/SCDbConclusion
Intracellular signaling 27 17 1.59 Overrepresented in IDDb 
Transcription factor 23 14 1.64 Overrepresented in IDDb 
Apoptosis 6.00 Overrepresented in IDDb 
Cell adhesion 0.14 Underrepresented in IDDb 
Transport 0.29 Underrepresented in IDDb 
Chromatin regulators 0.5 0.17 Underrepresented in IDDb 
Protein processing 0.5 0.07 Underrepresented in IDDb 
Protein synthesis 0.5 0.13 Underrepresented in IDDb 
Receptors 10 0.50 Underrepresented in IDDb 
Metabolism 10 13 0.77 Similar representation 
Unknown 17 NA NA Not comparable 
ProcessIDDb, %SCDb, %IDDb/SCDbConclusion
Intracellular signaling 27 17 1.59 Overrepresented in IDDb 
Transcription factor 23 14 1.64 Overrepresented in IDDb 
Apoptosis 6.00 Overrepresented in IDDb 
Cell adhesion 0.14 Underrepresented in IDDb 
Transport 0.29 Underrepresented in IDDb 
Chromatin regulators 0.5 0.17 Underrepresented in IDDb 
Protein processing 0.5 0.07 Underrepresented in IDDb 
Protein synthesis 0.5 0.13 Underrepresented in IDDb 
Receptors 10 0.50 Underrepresented in IDDb 
Metabolism 10 13 0.77 Similar representation 
Unknown 17 NA NA Not comparable 

Data of the stem cell database (SCDb) were derived from Ivanova et al.62 

NA indicates not applicable.

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