Genes associated with clonal dominance preferentially belong to three GO categories: intracellular signaling, transcription factor, and apoptosis
Process . | IDDb, % . | SCDb, % . | IDDb/SCDb . | Conclusion . |
---|---|---|---|---|
Intracellular signaling | 27 | 17 | 1.59 | Overrepresented in IDDb |
Transcription factor | 23 | 14 | 1.64 | Overrepresented in IDDb |
Apoptosis | 6 | 1 | 6.00 | Overrepresented in IDDb |
Cell adhesion | 1 | 7 | 0.14 | Underrepresented in IDDb |
Transport | 2 | 7 | 0.29 | Underrepresented in IDDb |
Chromatin regulators | 0.5 | 3 | 0.17 | Underrepresented in IDDb |
Protein processing | 0.5 | 7 | 0.07 | Underrepresented in IDDb |
Protein synthesis | 0.5 | 4 | 0.13 | Underrepresented in IDDb |
Receptors | 5 | 10 | 0.50 | Underrepresented in IDDb |
Metabolism | 10 | 13 | 0.77 | Similar representation |
Unknown | 17 | NA | NA | Not comparable |
Process . | IDDb, % . | SCDb, % . | IDDb/SCDb . | Conclusion . |
---|---|---|---|---|
Intracellular signaling | 27 | 17 | 1.59 | Overrepresented in IDDb |
Transcription factor | 23 | 14 | 1.64 | Overrepresented in IDDb |
Apoptosis | 6 | 1 | 6.00 | Overrepresented in IDDb |
Cell adhesion | 1 | 7 | 0.14 | Underrepresented in IDDb |
Transport | 2 | 7 | 0.29 | Underrepresented in IDDb |
Chromatin regulators | 0.5 | 3 | 0.17 | Underrepresented in IDDb |
Protein processing | 0.5 | 7 | 0.07 | Underrepresented in IDDb |
Protein synthesis | 0.5 | 4 | 0.13 | Underrepresented in IDDb |
Receptors | 5 | 10 | 0.50 | Underrepresented in IDDb |
Metabolism | 10 | 13 | 0.77 | Similar representation |
Unknown | 17 | NA | NA | Not comparable |
Data of the stem cell database (SCDb) were derived from Ivanova et al.62
NA indicates not applicable.