Table 2

Histopathologic and phenotypic characteristics of the 48 patients with nasal NK/T-cell lymphomas

CharacteristicNo. patients/total (%)
Angiocentric/angioinvasion pattern 39/48 (81) 
Epitheliotropism 37/48 (77) 
Necrosis 42/48 (87) 
Cytology  
    Small/medium 22/48 (46) 
    Medium/large 26/48 (54) 
CD3ε 48/48 (100) 
CD5 0/48 (0) 
CD56 38/48 (79) 
TiA1 32/32 (100) 
GrB 35/35 (100) 
EBV* 48/48 (100) 
CharacteristicNo. patients/total (%)
Angiocentric/angioinvasion pattern 39/48 (81) 
Epitheliotropism 37/48 (77) 
Necrosis 42/48 (87) 
Cytology  
    Small/medium 22/48 (46) 
    Medium/large 26/48 (54) 
CD3ε 48/48 (100) 
CD5 0/48 (0) 
CD56 38/48 (79) 
TiA1 32/32 (100) 
GrB 35/35 (100) 
EBV* 48/48 (100) 
*

EBV association was demonstrated by in situ hybridization in 47 cases and by LMP-1 immunostaining in 6 of 10 cases.

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