Table 4

Results of multivariable analysis for predictors of early mortality

VariablesN1/N2RR (95% CI)P
Conditioning regimen   < .001* 
    FLU-containing regimen 11/46 1.00  
    Non–FLU-containing regimen, T-cell–depleted grafts 17/26 4.19 (1.88-9.39) < .001 
    Non–FLU-containing regimen, non–T-cell-depleted grafts 15/24 5.11 (2.21-11.84) < .001 
Age at transplantation    
    10 years or younger 12/37 1.00  
    Older than 10 years 31/59 2.07 (1.03-4.15) .041 
Donor-recipient CMV status   .006 
    Donor negative/recipient negative 19/45 1.00  
    Donor positive/recipient negative 5/18 1.11 (0.40-3.09) .839 
    Donor negative/recipient positive 13/24 2.20 (1.07-4.52) .032 
    Donor positive/recipient positive 6/9 4.91 (1.83-13.19) .002 
VariablesN1/N2RR (95% CI)P
Conditioning regimen   < .001* 
    FLU-containing regimen 11/46 1.00  
    Non–FLU-containing regimen, T-cell–depleted grafts 17/26 4.19 (1.88-9.39) < .001 
    Non–FLU-containing regimen, non–T-cell-depleted grafts 15/24 5.11 (2.21-11.84) < .001 
Age at transplantation    
    10 years or younger 12/37 1.00  
    Older than 10 years 31/59 2.07 (1.03-4.15) .041 
Donor-recipient CMV status   .006 
    Donor negative/recipient negative 19/45 1.00  
    Donor positive/recipient negative 5/18 1.11 (0.40-3.09) .839 
    Donor negative/recipient positive 13/24 2.20 (1.07-4.52) .032 
    Donor positive/recipient positive 6/9 4.91 (1.83-13.19) .002 

N1 indicates number of early deaths; N2, number of evaluable patients; FLU, fludarabine.

*

Two-degree freedom test.

Three-degree freedom test.

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