Presenting characteristics of patients with acquired hemophilia A
| Characteristic (no. of patients for whom characteristic is known) . | No. of patients reported in 2-y study period for whom characteristic is known (%) . |
|---|---|
| Age category (154) | |
| 1 to less than 16 y | 1 (0.7) |
| 16 to less than 65 y | 22 (14.3) |
| 65 to less than 85 y | 97 (63.0) |
| 85 y and older | 34 (22.1) |
| Underlying diagnosis (150) | |
| None | 95 (63.33) |
| Autoimmune or collagen vascular disease | 25 (16.66) |
| Rheumatoid arthritis | 9 (6.00) |
| Polymyalgia rheumatica | 3 (2.00) |
| SLE | 3 (2.00) |
| Other | 10 (6.66) |
| Malignancy | 22 (14.66) |
| Lung | 5 (3.33) |
| Gastrointestinal | 5 (3.33) |
| Prostate | 3 (2.00) |
| Other | 8 (5.33) |
| Dermatologic | 5 (3.33) |
| Pemphigoid | 3 (2.00) |
| Other | 2 (1.33) |
| Pregnancy | 3 (2.00) |
| FVIII level category at diagnosis (154) | |
| Severe, 1 IU/dL or less | 46 (29.87) |
| Moderate, more than 1, less than 5 IU/dL | 56 (36.36) |
| Mild, 5 or more, less than 50 IU/dL | 52 (33.77) |
| Inhibitor titer category at diagnosis (144) | |
| 0-10 BU/mL | 9 (6.25) |
| 11-100 BU/mL | 119 (80.56) |
| 101-1000 BU/mL | 16 (11.11) |
| Sex (122) | |
| Female | 70 (57.38) |
| Male | 52 (42.62) |
| Center type (172) | |
| Comprehensive care hemophilia center | 93 (54.07) |
| Hemophilia center | 39 (22.67) |
| Nonhemophilia center | 40 (23.26) |
| Characteristic (no. of patients for whom characteristic is known) . | No. of patients reported in 2-y study period for whom characteristic is known (%) . |
|---|---|
| Age category (154) | |
| 1 to less than 16 y | 1 (0.7) |
| 16 to less than 65 y | 22 (14.3) |
| 65 to less than 85 y | 97 (63.0) |
| 85 y and older | 34 (22.1) |
| Underlying diagnosis (150) | |
| None | 95 (63.33) |
| Autoimmune or collagen vascular disease | 25 (16.66) |
| Rheumatoid arthritis | 9 (6.00) |
| Polymyalgia rheumatica | 3 (2.00) |
| SLE | 3 (2.00) |
| Other | 10 (6.66) |
| Malignancy | 22 (14.66) |
| Lung | 5 (3.33) |
| Gastrointestinal | 5 (3.33) |
| Prostate | 3 (2.00) |
| Other | 8 (5.33) |
| Dermatologic | 5 (3.33) |
| Pemphigoid | 3 (2.00) |
| Other | 2 (1.33) |
| Pregnancy | 3 (2.00) |
| FVIII level category at diagnosis (154) | |
| Severe, 1 IU/dL or less | 46 (29.87) |
| Moderate, more than 1, less than 5 IU/dL | 56 (36.36) |
| Mild, 5 or more, less than 50 IU/dL | 52 (33.77) |
| Inhibitor titer category at diagnosis (144) | |
| 0-10 BU/mL | 9 (6.25) |
| 11-100 BU/mL | 119 (80.56) |
| 101-1000 BU/mL | 16 (11.11) |
| Sex (122) | |
| Female | 70 (57.38) |
| Male | 52 (42.62) |
| Center type (172) | |
| Comprehensive care hemophilia center | 93 (54.07) |
| Hemophilia center | 39 (22.67) |
| Nonhemophilia center | 40 (23.26) |
Each characteristic is shown as an absolute number and a percentage of the patients on whom data were known for that characteristic. Age-specific incidence per million UK population per year: 1-< 16 y, 0.045; 16-< 65 y, 0.29; 65-< 85 y, 5.97; 85 y and older, 14.66.