Table 1

Thrombopoietic growth factors

First-generation thrombopoietic growth factors 
    Recombinant human thrombopoietins 
        rhTPO 
        PEG-rHuMGDF 
    Recombinant TPO fusion proteins 
        Promegapoietin (TPO/IL3 fusion protein) 
Second-generation thrombopoietic growth factors 
    TPO peptide mimetics 
        Fab 59 
        AMG 531 
        Peg-TPOmp 
    TPO nonpeptide mimetics 
        Eltrombopag (SB497115, Promacta) 
        AKR-501 
    TPO agonist antibodies 
        Minibodies [VB22B sc(Fv)2] 
        Domain subclass-converted TPO agonist antibodies (MA01G4G344) 
First-generation thrombopoietic growth factors 
    Recombinant human thrombopoietins 
        rhTPO 
        PEG-rHuMGDF 
    Recombinant TPO fusion proteins 
        Promegapoietin (TPO/IL3 fusion protein) 
Second-generation thrombopoietic growth factors 
    TPO peptide mimetics 
        Fab 59 
        AMG 531 
        Peg-TPOmp 
    TPO nonpeptide mimetics 
        Eltrombopag (SB497115, Promacta) 
        AKR-501 
    TPO agonist antibodies 
        Minibodies [VB22B sc(Fv)2] 
        Domain subclass-converted TPO agonist antibodies (MA01G4G344) 
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