Thrombocytosis |
Thrombosis |
Stimulation of tumor cell growth |
Stimulation of leukemia cell growth |
Interactions with other cytokines |
Autoantibody formation |
Stem cell depletion |
Reduction in threshold for platelet activation |
Increased bone marrow reticulin (positive reticulin stain) |
Increased bone marrow collagen (positive trichrome stain) |
Rebound worsening of thrombocytopenia upon stopping treatment |
Thrombocytosis |
Thrombosis |
Stimulation of tumor cell growth |
Stimulation of leukemia cell growth |
Interactions with other cytokines |
Autoantibody formation |
Stem cell depletion |
Reduction in threshold for platelet activation |
Increased bone marrow reticulin (positive reticulin stain) |
Increased bone marrow collagen (positive trichrome stain) |
Rebound worsening of thrombocytopenia upon stopping treatment |