Association of NZB phenotype and LPD
| Phenotype . | N . | Non-LPD (mean ± SD) . | N . | LPD (mean ± SD) . |
|---|---|---|---|---|
| Spleen | ||||
| Total | 128 | 391 ± 500 | 74 | 932 ± 937 |
| More than 500 (mg) | 31 | 1016 ± 699 | 41 | 1459 ± 975* |
| WBC | ||||
| Total | 106 | 6.7 ± 5.0 | 64 | 17.1 ± 34.0 |
| More than 20 (×106 cells/L) | 3 | 29.0 ± 5.2 | 11 | 65.3 ± 34.0* |
| RBC | ||||
| Total | 110 | 6.5 ± 2.0 | 64 | 5.8 ± 1.8 |
| Less than 4 (×109 cells/L) | 11 | 2.5 ± 0.5 | 7 | 2.3 ± 0.8 |
| MVC | ||||
| Total | 110 | 51.4 ± 12.0 | 64 | 53.5 ± 12.2 |
| More than 60 (fL) | 17 | 75.0 ± 11.6 | 11 | 76.0 ± 12.3 |
| IgM | ||||
| Total | 127 | 586 ± 206 | 71 | 577 ± 233 |
| More than 700 (mg/L) | 50 | 784.0 ± 43.5 | 29 | 814.4 ± 31.1 |
| RBC reticulocytes | ||||
| Total | 116 | 17.1 ± 29.1 | 70 | 17.2 ± 24.5 |
| More than 20* (%) | 24 | 68.1 ± 27.4 | 19 | 50.1 ± 26.3 |
| Phenotype . | N . | Non-LPD (mean ± SD) . | N . | LPD (mean ± SD) . |
|---|---|---|---|---|
| Spleen | ||||
| Total | 128 | 391 ± 500 | 74 | 932 ± 937 |
| More than 500 (mg) | 31 | 1016 ± 699 | 41 | 1459 ± 975* |
| WBC | ||||
| Total | 106 | 6.7 ± 5.0 | 64 | 17.1 ± 34.0 |
| More than 20 (×106 cells/L) | 3 | 29.0 ± 5.2 | 11 | 65.3 ± 34.0* |
| RBC | ||||
| Total | 110 | 6.5 ± 2.0 | 64 | 5.8 ± 1.8 |
| Less than 4 (×109 cells/L) | 11 | 2.5 ± 0.5 | 7 | 2.3 ± 0.8 |
| MVC | ||||
| Total | 110 | 51.4 ± 12.0 | 64 | 53.5 ± 12.2 |
| More than 60 (fL) | 17 | 75.0 ± 11.6 | 11 | 76.0 ± 12.3 |
| IgM | ||||
| Total | 127 | 586 ± 206 | 71 | 577 ± 233 |
| More than 700 (mg/L) | 50 | 784.0 ± 43.5 | 29 | 814.4 ± 31.1 |
| RBC reticulocytes | ||||
| Total | 116 | 17.1 ± 29.1 | 70 | 17.2 ± 24.5 |
| More than 20* (%) | 24 | 68.1 ± 27.4 | 19 | 50.1 ± 26.3 |
Significant difference between non-LPD and LPD, χ2 analysis P ≤ .001 (BD Biosciences, San Jose, CA).
N indicates number of mice.