Table 1

SAM-defined overexpressed genes in HMCLs expressing HPSE

ProbesetGene nameGene descriptionSAM score
219403_s_at HPSE Heparanase 1.82 
222881_at HPSE Heparanase 1.82 
230241_at IFRG15 Interferon responsive gene 15 1.82 
219253_at FAM11B Family with sequence similarity 11, member B 1.78 
227697_at SOCS3 Suppressor of cytokine signaling 3 1.78 
212037_at PNN Pinin, desmosome-associated protein 1.73 
HUMISGF3A_MA_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.73 
204908_s_at BCL3 B-cell CLL/lymphoma 3 1.65 
221876_at DKFZp762P2 Hypothetical protein DKFZp762P2111 1.65 
218935_at EHD3 EH-domain containing 3 1.65 
201316_at PSMA2 Proteasome (prosome macropain) subunit, alpha type 2 1.65 
HUMISGF3A_3_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.65 
212269_s_at MCM3AP Minichromosome maintenance deficient 3-associated protein 1.61 
201286_at SDC1 Syndecan-1 1.61 
238418_at SLC35B4 Solute carrier family 35, member B4 1.61 
209969_s_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.61 
230917_at — — 1.57 
227749_at — — 1.57 
202086_at MX1 Myxovirus resistance 1, interferon-inducible protein p78 (mouse) 1.57 
237942_at SNRK SNF related kinase 1.57 
HUMISGF3A_3_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.57 
237299_at — — 1.53 
221764_at C19ORF22 Chromosome 19 open reading frame 22 1.53 
217925_s_at C6ORF106 Chromosome 6 open reading frame 106 1.53 
201082_s_at DCTN1 Dynactin 1 (p150, glued homolog, Drosophila1.53 
206662_at GLRX Glutaredoxin (thioltransferase) 1.53 
227713_at KATNAL1 Katanin p60 subunit A-like 1 1.53 
225752_at NIPA1 Nonimprinted in Prader-Willi/Angelman syndrome 1 1.53 
201964_at ALS4 Amyotrophic lateral sclerosis 4; juvenile 1.49 
207522_s_at ATP2A3 ATPase, Ca++ transporting, ubiquitous 1.49 
236831_at C3orf6 Chromosome 3 open reading frame 6 1.49 
239629_at CFLAR CASP8 and FADD-like apoptosis regulator 1.49 
225097_at HIPK2 Homeodomain interacting protein kinase 2 1.49 
211824_x_at NALP1 NACHT, leucine rich repeat and PYD containing 1 1.49 
213241_at PLXNC1 Plexin C1 1.49 
226782_at SLC25A30 Solute carrier family 25, member 30 1.49 
235035_at SLC35E1 Solute carrier family 35, member E1 1.49 
212926_at SMC5L1 SMC5 structural maintenance of chromosomes 5-like 1 (yeast) 1.49 
HUMISGF3A_MA_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.49 
200887_s_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.49 
209197_at SYT11 Synaptotagmin XI 1.49 
ProbesetGene nameGene descriptionSAM score
219403_s_at HPSE Heparanase 1.82 
222881_at HPSE Heparanase 1.82 
230241_at IFRG15 Interferon responsive gene 15 1.82 
219253_at FAM11B Family with sequence similarity 11, member B 1.78 
227697_at SOCS3 Suppressor of cytokine signaling 3 1.78 
212037_at PNN Pinin, desmosome-associated protein 1.73 
HUMISGF3A_MA_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.73 
204908_s_at BCL3 B-cell CLL/lymphoma 3 1.65 
221876_at DKFZp762P2 Hypothetical protein DKFZp762P2111 1.65 
218935_at EHD3 EH-domain containing 3 1.65 
201316_at PSMA2 Proteasome (prosome macropain) subunit, alpha type 2 1.65 
HUMISGF3A_3_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.65 
212269_s_at MCM3AP Minichromosome maintenance deficient 3-associated protein 1.61 
201286_at SDC1 Syndecan-1 1.61 
238418_at SLC35B4 Solute carrier family 35, member B4 1.61 
209969_s_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.61 
230917_at — — 1.57 
227749_at — — 1.57 
202086_at MX1 Myxovirus resistance 1, interferon-inducible protein p78 (mouse) 1.57 
237942_at SNRK SNF related kinase 1.57 
HUMISGF3A_3_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.57 
237299_at — — 1.53 
221764_at C19ORF22 Chromosome 19 open reading frame 22 1.53 
217925_s_at C6ORF106 Chromosome 6 open reading frame 106 1.53 
201082_s_at DCTN1 Dynactin 1 (p150, glued homolog, Drosophila1.53 
206662_at GLRX Glutaredoxin (thioltransferase) 1.53 
227713_at KATNAL1 Katanin p60 subunit A-like 1 1.53 
225752_at NIPA1 Nonimprinted in Prader-Willi/Angelman syndrome 1 1.53 
201964_at ALS4 Amyotrophic lateral sclerosis 4; juvenile 1.49 
207522_s_at ATP2A3 ATPase, Ca++ transporting, ubiquitous 1.49 
236831_at C3orf6 Chromosome 3 open reading frame 6 1.49 
239629_at CFLAR CASP8 and FADD-like apoptosis regulator 1.49 
225097_at HIPK2 Homeodomain interacting protein kinase 2 1.49 
211824_x_at NALP1 NACHT, leucine rich repeat and PYD containing 1 1.49 
213241_at PLXNC1 Plexin C1 1.49 
226782_at SLC25A30 Solute carrier family 25, member 30 1.49 
235035_at SLC35E1 Solute carrier family 35, member E1 1.49 
212926_at SMC5L1 SMC5 structural maintenance of chromosomes 5-like 1 (yeast) 1.49 
HUMISGF3A_MA_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.49 
200887_s_at STAT1 Signal transducer and activator of transcription 1, 91 kDa 1.49 
209197_at SYT11 Synaptotagmin XI 1.49 

These data are the 41 probesets overexpressed at least 2-fold in the 11 HPSEpos HMCLs compared with the 8 HPSEneg HMCLs (SAM analysis with a FDR of 7.7%). Genes are ordered based on the SAM score.

— indicates Expressed Sequence Tags (EST).

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