GO categories discriminating among hierarchical cluster-defined CBF subgroups
| GO description . | GO category . | No. of genes . | LS permutation . | KS permutation . |
|---|---|---|---|---|
| Spindle pole | 922 | 22 | <.001 | <.001 |
| Spindle | 5819 | 34 | <.001 | <.001 |
| ATP-dependent helicase activity | 8026 | 35 | <.001 | <.001 |
| DNA-dependent ATPase activity | 8094 | 17 | <.001 | .021 |
| Small protein conjugating enzyme activity | 8639 | 27 | <.001 | .006 |
| M phase of mitotic cell cycle | 87 | 96 | <.001 | <.001 |
| RNA splicing via transesterification reactions | 375 | 51 | <.001 | <.001 |
| RNA splicing | 377 | 51 | <.001 | <.001 |
| Nuclear mRNA splicing via spliceosome | 398 | 51 | <.001 | <.001 |
| mRNA processing | 6397 | 81 | <.001 | <.001 |
| Mitosis | 7067 | 96 | <.001 | <.001 |
| RNA splicing | 8380 | 71 | <.001 | <.001 |
| mRNA metabolism | 16071 | 90 | <.001 | <.001 |
| Centrosome | 5813 | 20 | <.001 | .001 |
| Ubiquitin-dependent protein catabolism | 6511 | 47 | <.001 | .004 |
| Modification-dependent protein catabolism | 19941 | 47 | <.001 | .004 |
| Ubiquitin conjugating enzyme activity | 4840 | 26 | <.001 | .008 |
| Dynein complex | 30286 | 11 | <.001 | .074 |
| Damaged DNA binding | 3684 | 22 | <.001 | .004 |
| Microtubule organizing center | 5815 | 22 | <.001 | .002 |
| Cytokinesis | 910 | 92 | <.001 | .017 |
| Cell division | 51301 | 92 | <.001 | .017 |
| RNA helicase activity | 3724 | 13 | <.001 | <.001 |
| Cytoplasmic dynein complex | 5868 | 8 | <.001 | .033 |
| Ubiquitin-specific protease activity | 4843 | 29 | <.001 | .01901 |
| Ubiquitin thiolesterase activity | 4221 | 25 | <.001 | .005 |
| Thiolester hydrolase activity | 16790 | 29 | <.001 | .006 |
| Microtubule cytoskeleton | 15630 | 79 | <.001 | .012 |
| Nucleoplasm | 5654 | 93 | <.001 | .005 |
| Spindle organization and biogenesis | 7051 | 11 | <.001 | .037 |
| Mitotic spindle organization and biogenesis | 7052 | 11 | <.001 | .037 |
| Microtubule cytoskeleton organization and biogenesis | 226 | 23 | .002 | <.001 |
| Microtubule-based process | 7017 | 60 | .004 | <.001 |
| MAPK | 4707 | 14 | .016 | <.001 |
| Ribonuclease activity | 4540 | 19 | .017 | <.001 |
| Gluconeogenesis | 6094 | 9 | .034 | <.001 |
| Pyruvate metabolism | 6090 | 10 | .048 | <.001 |
| GO description . | GO category . | No. of genes . | LS permutation . | KS permutation . |
|---|---|---|---|---|
| Spindle pole | 922 | 22 | <.001 | <.001 |
| Spindle | 5819 | 34 | <.001 | <.001 |
| ATP-dependent helicase activity | 8026 | 35 | <.001 | <.001 |
| DNA-dependent ATPase activity | 8094 | 17 | <.001 | .021 |
| Small protein conjugating enzyme activity | 8639 | 27 | <.001 | .006 |
| M phase of mitotic cell cycle | 87 | 96 | <.001 | <.001 |
| RNA splicing via transesterification reactions | 375 | 51 | <.001 | <.001 |
| RNA splicing | 377 | 51 | <.001 | <.001 |
| Nuclear mRNA splicing via spliceosome | 398 | 51 | <.001 | <.001 |
| mRNA processing | 6397 | 81 | <.001 | <.001 |
| Mitosis | 7067 | 96 | <.001 | <.001 |
| RNA splicing | 8380 | 71 | <.001 | <.001 |
| mRNA metabolism | 16071 | 90 | <.001 | <.001 |
| Centrosome | 5813 | 20 | <.001 | .001 |
| Ubiquitin-dependent protein catabolism | 6511 | 47 | <.001 | .004 |
| Modification-dependent protein catabolism | 19941 | 47 | <.001 | .004 |
| Ubiquitin conjugating enzyme activity | 4840 | 26 | <.001 | .008 |
| Dynein complex | 30286 | 11 | <.001 | .074 |
| Damaged DNA binding | 3684 | 22 | <.001 | .004 |
| Microtubule organizing center | 5815 | 22 | <.001 | .002 |
| Cytokinesis | 910 | 92 | <.001 | .017 |
| Cell division | 51301 | 92 | <.001 | .017 |
| RNA helicase activity | 3724 | 13 | <.001 | <.001 |
| Cytoplasmic dynein complex | 5868 | 8 | <.001 | .033 |
| Ubiquitin-specific protease activity | 4843 | 29 | <.001 | .01901 |
| Ubiquitin thiolesterase activity | 4221 | 25 | <.001 | .005 |
| Thiolester hydrolase activity | 16790 | 29 | <.001 | .006 |
| Microtubule cytoskeleton | 15630 | 79 | <.001 | .012 |
| Nucleoplasm | 5654 | 93 | <.001 | .005 |
| Spindle organization and biogenesis | 7051 | 11 | <.001 | .037 |
| Mitotic spindle organization and biogenesis | 7052 | 11 | <.001 | .037 |
| Microtubule cytoskeleton organization and biogenesis | 226 | 23 | .002 | <.001 |
| Microtubule-based process | 7017 | 60 | .004 | <.001 |
| MAPK | 4707 | 14 | .016 | <.001 |
| Ribonuclease activity | 4540 | 19 | .017 | <.001 |
| Gluconeogenesis | 6094 | 9 | .034 | <.001 |
| Pyruvate metabolism | 6090 | 10 | .048 | <.001 |
Number of genes used for random variance estimation: 8556; number of investigated GO categories: 1545; table sorted by P value of the LS permutation test; 37 GO categories are significant at the nominal .001 level of the LS permutation test or KS permutation test.