Table 4

Univariate Cox proportional hazards models for survival

VariableRelative risk95% CIP
Age, y 1.05 1.04-1.06 < .001* 
Ln WBC count 1.37 1.23-1.53 < .001* 
ALC 1.59 1.39-1.83 < .001* 
HGB 0.84 0.80-0.88 < .001* 
PLT count 0.998 0.997-1.00 .01* 
β-2M 1.29 1.25-1.34 < .001* 
Ln ALB 0.07 0.04-0.13 < .001* 
Ln Alk Phos 2.75 2.11-3.60 < .001* 
Ln LDH 2.50 1.96-3.18 < .001* 
Ln prolymphs 1.28 1.13-1.46 .001* 
BM lymphs 1.01 1.01-1.02 < .001* 
BM cellularity 1.01 1.01-1.02 < .001* 
Ln spleen size 1.31 1.17-1.46 < .001* 
Ln liver size 1.64 1.34-2.00 < .001* 
Ln IgG 1.04 0.81-1.33 .76 
Ln IgA 0.85 0.75-0.97 .02* 
Ln IgM 0.93 0.81-1.07 .32 
Time from Dx to MDACC 1.04 1.01-1.08 .02* 
VariableRelative risk95% CIP
Age, y 1.05 1.04-1.06 < .001* 
Ln WBC count 1.37 1.23-1.53 < .001* 
ALC 1.59 1.39-1.83 < .001* 
HGB 0.84 0.80-0.88 < .001* 
PLT count 0.998 0.997-1.00 .01* 
β-2M 1.29 1.25-1.34 < .001* 
Ln ALB 0.07 0.04-0.13 < .001* 
Ln Alk Phos 2.75 2.11-3.60 < .001* 
Ln LDH 2.50 1.96-3.18 < .001* 
Ln prolymphs 1.28 1.13-1.46 .001* 
BM lymphs 1.01 1.01-1.02 < .001* 
BM cellularity 1.01 1.01-1.02 < .001* 
Ln spleen size 1.31 1.17-1.46 < .001* 
Ln liver size 1.64 1.34-2.00 < .001* 
Ln IgG 1.04 0.81-1.33 .76 
Ln IgA 0.85 0.75-0.97 .02* 
Ln IgM 0.93 0.81-1.07 .32 
Time from Dx to MDACC 1.04 1.01-1.08 .02* 

CI indicates confidence interval; Ln, natural log; WBC, white blood cell; ALC, absolute lymphocyte count; HGB, hemoglobin; PLT, platelet; β-2M, β-2 microglobulin; ALB, albumin; Alk Phos, alkaline phosphatase; LDH, lactate dehydrogenase; BM lymphs, bone marrow lymphocytes; prolymphs, prolymphocytes; Dx, diagnosis; MDACC, M. D. Anderson Cancer Center.

*

Statistically significant.

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