Table 3

Summary of protein macroarray data (human fetal brain cDNA library) from the CLL mAb screening

CLL antibody/proteinQualityClone ID
CII/IGHV1-69UM subset-5   
    Proline-rich acidic protein 1 MPMGp800H11522 
    Proline-rich acidic protein 1 MPMGp800L07522 
    Igλ-like polypeptide 1 isoform b precursor MPMGp800L22599 
    Cofilin 1 (nonmuscle) ± MPMGp800F21524 
    Mannosidase, alpha, class 2C, member 1 ± MPMGp800E09593 
    Predicted: similar to tripartite motif protein 11 ± MPMGp800F21600 
232B4/IGHV3-48M   
    Cofilin 1 (nonmuscle) ++ MPMGp800F21524 
    Cleavage and polyadenylation specific factor 5 ± MPMGp800N01597 
    Predicted: similar to tripartite motif protein 11 ± MPMGp800F21600 
    Igλ-like polypeptide 1 isoform b precursor ± MPMGp800L22599 
rIGHV3-21M subset-2   
    Cofilin 1 (nonmuscle) ++ MPMGp800F21524 
    Cleavage and polyadenylation specific factor 5 MPMGp800N01597 
    Signal peptide peptidase-like 2B isoform 2 ± MPMGp800M20598 
    Igλ-like polypeptide 1 isoform b precursor ± MPMGp800L22599 
CLL antibody/proteinQualityClone ID
CII/IGHV1-69UM subset-5   
    Proline-rich acidic protein 1 MPMGp800H11522 
    Proline-rich acidic protein 1 MPMGp800L07522 
    Igλ-like polypeptide 1 isoform b precursor MPMGp800L22599 
    Cofilin 1 (nonmuscle) ± MPMGp800F21524 
    Mannosidase, alpha, class 2C, member 1 ± MPMGp800E09593 
    Predicted: similar to tripartite motif protein 11 ± MPMGp800F21600 
232B4/IGHV3-48M   
    Cofilin 1 (nonmuscle) ++ MPMGp800F21524 
    Cleavage and polyadenylation specific factor 5 ± MPMGp800N01597 
    Predicted: similar to tripartite motif protein 11 ± MPMGp800F21600 
    Igλ-like polypeptide 1 isoform b precursor ± MPMGp800L22599 
rIGHV3-21M subset-2   
    Cofilin 1 (nonmuscle) ++ MPMGp800F21524 
    Cleavage and polyadenylation specific factor 5 MPMGp800N01597 
    Signal peptide peptidase-like 2B isoform 2 ± MPMGp800M20598 
    Igλ-like polypeptide 1 isoform b precursor ± MPMGp800L22599 

Ab-binding quality/strengths are ++, +, and ±.

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