Quantification of ultrastructural features of VAMP-8+/+ and VAMP-8−/− BMMCs
Mice and experiments . | Granule size, % small granules . | No. of SGs/cell, mean plus or minus SEM . | No. of immature* SGs/cell, mean plus or minus SEM . |
---|---|---|---|
VAMP-8 WT | |||
Exp 1, n = 47 | 60 | 43.4 ± 3.0 | 9.3 ± 1.2† |
Exp 2, n = 25 | 65 | 22.3 ± 2.5 | 9.1 ± 2.3† |
VAMP-8 deficient | |||
Exp 1, n = 59 | 61 | 36.0 ± 3.0 | 5.8 ± 0.56 |
Exp 2, n = 42 | 59 | 22.6 ± 1.8 | 5.3 ± 1.00 |
Mice and experiments . | Granule size, % small granules . | No. of SGs/cell, mean plus or minus SEM . | No. of immature* SGs/cell, mean plus or minus SEM . |
---|---|---|---|
VAMP-8 WT | |||
Exp 1, n = 47 | 60 | 43.4 ± 3.0 | 9.3 ± 1.2† |
Exp 2, n = 25 | 65 | 22.3 ± 2.5 | 9.1 ± 2.3† |
VAMP-8 deficient | |||
Exp 1, n = 59 | 61 | 36.0 ± 3.0 | 5.8 ± 0.56 |
Exp 2, n = 42 | 59 | 22.6 ± 1.8 | 5.3 ± 1.00 |