Table 4 Multivariate analysis according... | American Society of Hematology

Table 4

Multivariate analysis according to type of induction death

Covariate	Unfavorable category	Induction death		Cause of death
		Induction death		Hemorrhage		Infection		Differentiation syndrome
		OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Creatinine level	Abnormal levels	23.8 (6.3-89.2)	<.001	24.3 (7.5-78.1)	<.001	—	.29	—	.22
WBC count, × 10⁹/L	10 or higher	2.2 (1.1-4.6)	.04	—	.12	—	.21	—	.49
PB blast count, × 10⁹/L	30 or higher	3.3 (1.4-7.9)	<.001	4.4 (1.9-10.2)	<.001	—	.13	—	.85
Age, y	60 years or older	4.4 (2.4-8.1)	<.001	—	.14	11.0 (3.9-31.4)	<.001	—	.56
Sex	Male	2.8 (1.5-5.2)	<.001	—	.16	5.1 (1.4-18.3)	.003	—	.61
Coagulopathy at presentation	Yes	—	.21	3.3 (0.97-11.6)	.03	—	.78	—	.88
Fever at presentation	Yes	—	.49	—	.85	3.9 (1.3-11.7)	.009	—	.47
ECOG score	At least 2	—	.45	—	.86	—	.98	4.5 (1.2-17.2)	.009
Albumin level	Abnormal levels	—	.11	—	.62	—	.52	4.1 (1.1-16.1)	.045

Covariate	Unfavorable category	Induction death		Cause of death
		Induction death		Hemorrhage		Infection		Differentiation syndrome
		OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Creatinine level	Abnormal levels	23.8 (6.3-89.2)	<.001	24.3 (7.5-78.1)	<.001	—	.29	—	.22
WBC count, × 10⁹/L	10 or higher	2.2 (1.1-4.6)	.04	—	.12	—	.21	—	.49
PB blast count, × 10⁹/L	30 or higher	3.3 (1.4-7.9)	<.001	4.4 (1.9-10.2)	<.001	—	.13	—	.85
Age, y	60 years or older	4.4 (2.4-8.1)	<.001	—	.14	11.0 (3.9-31.4)	<.001	—	.56
Sex	Male	2.8 (1.5-5.2)	<.001	—	.16	5.1 (1.4-18.3)	.003	—	.61
Coagulopathy at presentation	Yes	—	.21	3.3 (0.97-11.6)	.03	—	.78	—	.88
Fever at presentation	Yes	—	.49	—	.85	3.9 (1.3-11.7)	.009	—	.47
ECOG score	At least 2	—	.45	—	.86	—	.98	4.5 (1.2-17.2)	.009
Albumin level	Abnormal levels	—	.11	—	.62	—	.52	4.1 (1.1-16.1)	.045

OR indicates odds ratio; WBC, white blood cell; PB, peripheral blood; ECOG, Eastern Cooperative Oncology Group; and —, not applicable.