Table 1 Somatic copy number alterations... | American Society of Hematology

Table 1

Somatic copy number alterations at diagnosis and relapse in 20 childhood B-precursor ALL cases

ID	Gains			Losses			Copy number alterations			Race	Age at diagnosis, y	Sex	Time to relapse, mo
ID	Diagnosis	Relapse	Shared	Diagnosis	Relapse	Shared	Diagnosis	Relapse	Shared*	Race	Age at diagnosis, y	Sex	Time to relapse, mo
1	3	4	3	0	3	0	3	7	3	White	6.9	Male	39.0
2†	10	10	10	2	2	2	12	12	12	Hispanic	8	Male	20.1
3	2	2	2	3	4	3	5	6	5	White	7.3	Female	21.8
4†	14	14	14	70	70	70	84	84	84	Hispanic	5.6	Male	52.2
5	2	4	2	15	18	14	17	22	16	Hispanic	18.3	Male	41.0
6†	5	5	5	1	4	1	6	9	6	White	3.4	Female	21.2
7	1	3	1	8	8	8	9	11	9	White	9.8	Male	12.6
8	0	1	0	11	13	11	11	14	11	Hispanic	12.2	Female	34.9
9	0	1	0	19	21	19	19	22	19	White	7.7	Male	10.6
10	0	0	0	6	7	5	6	7	5	White	1.9	Female	37.8
11	0	0	0	9	8	7	9	8	7	White	12	Female	49.6
12	3	3	3	9	10	9	12	13	12	White	7.6	Female	21.7
13	1	1	1	9	11	8	10	12	9	White	14.3	Male	19.1
14	4	4	4	9	7	7	13	11	11	White	8.4	Female	30.3
15	1	2	1	38	31	14	39	33	15	White	12.6	Male	17.2
16	13	19	13	25	29	25	38	48	38	White	5.7	Male	14.7
17	4	4	4	10	9	9	14	13	13	White	2.4	Male	13.3
18	2	2	2	3	3	3	5	5	5	Black	9.3	Female	7.6
19‡	4	12	2	21	22	21	25	34	23	White	5.9	Male	10.6
20	5	4	4	20	21	20	25	25	24	White	11.9	Male	10.3
Total	74	95	71	288	301	256	362	396	327

ID	Gains			Losses			Copy number alterations			Race	Age at diagnosis, y	Sex	Time to relapse, mo
ID	Diagnosis	Relapse	Shared	Diagnosis	Relapse	Shared	Diagnosis	Relapse	Shared*	Race	Age at diagnosis, y	Sex	Time to relapse, mo
1	3	4	3	0	3	0	3	7	3	White	6.9	Male	39.0
2†	10	10	10	2	2	2	12	12	12	Hispanic	8	Male	20.1
3	2	2	2	3	4	3	5	6	5	White	7.3	Female	21.8
4†	14	14	14	70	70	70	84	84	84	Hispanic	5.6	Male	52.2
5	2	4	2	15	18	14	17	22	16	Hispanic	18.3	Male	41.0
6†	5	5	5	1	4	1	6	9	6	White	3.4	Female	21.2
7	1	3	1	8	8	8	9	11	9	White	9.8	Male	12.6
8	0	1	0	11	13	11	11	14	11	Hispanic	12.2	Female	34.9
9	0	1	0	19	21	19	19	22	19	White	7.7	Male	10.6
10	0	0	0	6	7	5	6	7	5	White	1.9	Female	37.8
11	0	0	0	9	8	7	9	8	7	White	12	Female	49.6
12	3	3	3	9	10	9	12	13	12	White	7.6	Female	21.7
13	1	1	1	9	11	8	10	12	9	White	14.3	Male	19.1
14	4	4	4	9	7	7	13	11	11	White	8.4	Female	30.3
15	1	2	1	38	31	14	39	33	15	White	12.6	Male	17.2
16	13	19	13	25	29	25	38	48	38	White	5.7	Male	14.7
17	4	4	4	10	9	9	14	13	13	White	2.4	Male	13.3
18	2	2	2	3	3	3	5	5	5	Black	9.3	Female	7.6
19‡	4	12	2	21	22	21	25	34	23	White	5.9	Male	10.6
20	5	4	4	20	21	20	25	25	24	White	11.9	Male	10.3
Total	74	95	71	288	301	256	362	396	327

Shared CNAs were defined as diagnosis lesions that were also present at relapse.

Hyperdiploidy (> 50) at both diagnosis and relapse.

Hyperdiploidy (> 50) at relapse.