Table 1

Genes whose expression in monoclonal CD4+ T-LGL cells significantly (P < .006) changed after short-term in vitro hCMV stimulation

Probe setGene symbolScoreGene description
211748_x_at PTGDS 10,13416371 Prostaglandin D2 synthase 21 kDa (brain) 
244813_at RAD51L1 7,676334816 RAD51-like 1 (S cerevisiae
213915_at NKG7 7,649233005 Natural killer cell group 7 sequence 
215898_at TTLL5 7,324824305 Tubulin tyrosine ligase-like family, member 5 
206026_s_at TNFAIP6 7,270728576 Tumor necrosis factor, alpha-induced protein 6 
219023_at C4orf16 7,237962005 Chromosome 4 open reading frame 16 
222858_s_at DAPP1 6,933745384 Dual adaptor of phosphotyrosine and 3-phosphoinositides 
223484_at C15orf48 6,916996754 Chromosome 15 open reading frame 48 
208184_s_at TMEM1 6,71864243 Transmembrane protein 1 
214038_at CCL8 6,110026344 Chemokine (C-C motif) ligand 8 
209799_at PRKAA1 5,895332958 Protein kinase, AMP-activated, alpha 1 catalytic subunit 
231577_s_at GBP1 5,876037622 Quanylate binding protein 1, interferon-inducible, 67 kDa 
213002_at MARCKS 5,841826371 Myristoylated alanine-rich protein kinase C substrate 
205159_at CSF2RB 5,826684303 Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 
230012_at C17orf44 5,810899214 Chromosome 17 open reading frame 44 
205267_at POU2AF1 5,7541994 POU domain, class 2, associating factor 1 
222388_s_at VPS35 5,750463855 Vacuolar protein sorting 35 (yeast) 
1554885_a_at PRIM2A 5,734193947 Primase, polypeptide 2A, 58 kDa 
223382_s_at ZNRF1 5,700054082 Zinc and ring finger 1 
41469_at PI3 5,667143829 Peptidase inhibitor 3, skin-derived (SKALP) 
229344_x_at FAM80B 5,615111734 Family with sequence similarity 80, member B 
218096_at AGPAT5 5,548067875 1-Acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) 
241917_at FCHSD2 5,544997567 FCH and double SH3 domains 2 
1555884_at PSMD6 5,462286485 Proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 
243512_x_at IMMP2L 5,43440168 IMP2 inner mitochondrial membrane peptidase-like (S cerevisiae
222833_at CAPNS2 5,404156833 Calpain, small subunit 2 
204533_at CXCL10 5,397907696 Chemokine (C-X-C motif) ligand 10 
230434_at KLHL23 5,367623661 Kelch-like 23 (Drosophila) 
222845_x_at TMBIM4 5,36183547 Transmembrane BAX inhibitor motif containing 4 
205283_at FCMD 5,330492853 Fukuyama-type congenital muscular dystrophy (fukutin) 
1554929_at KIAA0999 5,297695496 NA 
52159_at HEMK1 5,293319745 HemK methyltransferase family member 1 
224827_at DC-UbP 5,210263204 NA 
205641_s_at TRADD 5,19931747 TNFRSF1A-associated via death domain 
201295_s_at WSB1 5,191526754 WD repeat and SOCS box-containing 1 
218507_at HIG2 5,175505974 NA 
222386_s_at COPZ1 5,174500241 Coatomer protein complex, subunit zeta 1 
204057_at IRF8 5,165308859 Interferon regulatory factor 8 
218562_s_at TMEM57 5,163304991 Transmembrane protein 57 
221059_s_at CHST6 5,152533315 Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 
209969_s_at STAT1 5,083186457 Signal transducer and activator of transcription 1, 91 kDa 
232027_at SYNE1 5,031819366 Spectrin repeat containing, nuclear envelope 1 
204633_s_at RPS6KA5 5,023419317 Ribosomal protein S6 kinase, 90 kDa, polypeptide 5 
216841_s_at SOD2 5,017952939 Superoxide dismutase 2, mitochondrial 
222691_at SLC35B3 5,009110445 Solute carrier family 35, member B3 
207700_s_at NCOA3 4,974277498 Nuclear receptor coactivator 3 
235574_at GBP4 4,96365421 Guanylate binding protein 4 
222045_s_at C20orf67 4,935840305 Chromosome 20 open reading frame 67 
204500_s_at AGTPBP1 4,934205697 ATP/GTP binding protein 1 
1556967_at ZDHHC14 4,92755238 Zinc finger, DHHC-type containing 14 
204613_at PLCG2 4,924269359 Phospholipase C, gamma 2 (phosphatidylinositol-specific) 
212378_at GART 4,924160286 Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 
210050_at TPI1 4,920823757 Triosephosphate isomerase 1 
204125_at NDUFAF1 4,920466452 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1 
204068_at STK3 4,894787293 Serine/threonine kinase 3 (STE20 homolog, yeast) 
201900_s_at AKR1A1 4,890038496 Aldo-keto reductase family 1, member A1 (aldehyde reductase) 
242939_at TFDP1 4,889767365 Transcription factor Dp-1 
226511_at MCART1 4,864612596 Mitochondrial carrier triple repeat 1 
201921_at LOC552891 4,824421802 NA 
223767_at GPR84 4,819947478 G protein-coupled receptor 84 
204565_at THEM2 4,79843566 Thioesterase superfamily member 2 
229398_at RAB18 4,788964099 RAB18, member RAS oncogene family 
227458_at C9orf46 4,769116802 Chromosome 9 open reading frame 46 
206584_at LY96 4,766515038 Lymphocyte antigen 96 
213246_at C14orf130 4,765949714 Chromosome 14 open reading frame 130 
213246_at C14orf130 4,765949714 Chromosome 14 open reading frame 130 
203518_at LYST 4,755336993 Lysosomal trafficking regulador 
236717_at LOC165186 4,713732588 NA 
226170_at EYA3 4,699440582 Eyes absent homolog 3 (Drosophila) 
212442_s_at LASS6 4,673946958 LAG1 longevity assurance homolog 6 (S. cerevisiae) 
227247_at PLEKHA8 4,640609475 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 
201463_s_at TALDO1 4,623771225 Transaldolase 1 
204702_s_at NFE2L3 4,608324388 Nuclear factor (erythroid-derived 2)-like 3 
224445_s_at ZFYVE21 4,60690338 Zinc finger, FYVE domain containing 21 
204446_s_at ALOX5 4,606635061 Arachidonate 5-lipoxygenase 
206478_at KIAA0125 4,604412442 KIAA0125 
215380_s_at C7orf24 4,59977998 Chromosome 7 open reading frame 24 
218230_at ARFIP1 4,584558778 ADP-ribosylation factor interacting protein 1 (arfaptin 1) 
229500_at SLC30A9 4,576485193 Solute carrier family 30 (zinc transporter), member 9 
209222_s_at OSBPL2 4,567763881 Oxysterol binding protein-like 2 
206267_s_at MATK 4,558282396 Megakaryocyte-associated tyrosine kinase 
214681_at GK 4,538965602 Glycerol kinase 
228106_at C4orf30 4,537274088 Chromosome 4 open reading frame 30 
218095_s_at TMEM165 4,527525331 Transmembrane protein 165 
212961_x_at CXorf40B 4,521246647 Chromosome X open reading frame 40B 
227438_at ALPK1 4,516024032 Alpha-kinase 1 
210347_s_at BCL11A 4,513152919 B-cell CLL/lymphoma 11A (zinc finger protein) 
206637_at P2RY14 4,513063383 Purinergic receptor P2Y, G-protein coupled, 14 
1561167_at ETV6 4,500052398 ets variant gene 6 (TEL oncogene) 
204254_s_at VDR 4,498636497 Vitamin D (1,25- dihydroxyvitamin D3) receptor 
206995_x_at SCARF1 4,491153208 Scavenger receptor class F, member 1 
201328_at ETS2 4,487520459 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) 
221843_s_at KIAA1609 4,485591378 KIAA1609 
207426_s_at TNFSF4 4,483796011 Tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34 kDa) 
236995_x_at TFEC 4,482801297 Transcription factor EC 
209238_at STX3 4,468215629 Syntaxin 3 
40016_g_at MAST4 4,464348703 Microtubule associated serine/threonine kinase family member 4 
222357_at ZBTB20 4,452512078 Zinc finger and BTB domain containing 20 
Probe setGene symbolScoreGene description
211748_x_at PTGDS 10,13416371 Prostaglandin D2 synthase 21 kDa (brain) 
244813_at RAD51L1 7,676334816 RAD51-like 1 (S cerevisiae
213915_at NKG7 7,649233005 Natural killer cell group 7 sequence 
215898_at TTLL5 7,324824305 Tubulin tyrosine ligase-like family, member 5 
206026_s_at TNFAIP6 7,270728576 Tumor necrosis factor, alpha-induced protein 6 
219023_at C4orf16 7,237962005 Chromosome 4 open reading frame 16 
222858_s_at DAPP1 6,933745384 Dual adaptor of phosphotyrosine and 3-phosphoinositides 
223484_at C15orf48 6,916996754 Chromosome 15 open reading frame 48 
208184_s_at TMEM1 6,71864243 Transmembrane protein 1 
214038_at CCL8 6,110026344 Chemokine (C-C motif) ligand 8 
209799_at PRKAA1 5,895332958 Protein kinase, AMP-activated, alpha 1 catalytic subunit 
231577_s_at GBP1 5,876037622 Quanylate binding protein 1, interferon-inducible, 67 kDa 
213002_at MARCKS 5,841826371 Myristoylated alanine-rich protein kinase C substrate 
205159_at CSF2RB 5,826684303 Colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 
230012_at C17orf44 5,810899214 Chromosome 17 open reading frame 44 
205267_at POU2AF1 5,7541994 POU domain, class 2, associating factor 1 
222388_s_at VPS35 5,750463855 Vacuolar protein sorting 35 (yeast) 
1554885_a_at PRIM2A 5,734193947 Primase, polypeptide 2A, 58 kDa 
223382_s_at ZNRF1 5,700054082 Zinc and ring finger 1 
41469_at PI3 5,667143829 Peptidase inhibitor 3, skin-derived (SKALP) 
229344_x_at FAM80B 5,615111734 Family with sequence similarity 80, member B 
218096_at AGPAT5 5,548067875 1-Acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon) 
241917_at FCHSD2 5,544997567 FCH and double SH3 domains 2 
1555884_at PSMD6 5,462286485 Proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 
243512_x_at IMMP2L 5,43440168 IMP2 inner mitochondrial membrane peptidase-like (S cerevisiae
222833_at CAPNS2 5,404156833 Calpain, small subunit 2 
204533_at CXCL10 5,397907696 Chemokine (C-X-C motif) ligand 10 
230434_at KLHL23 5,367623661 Kelch-like 23 (Drosophila) 
222845_x_at TMBIM4 5,36183547 Transmembrane BAX inhibitor motif containing 4 
205283_at FCMD 5,330492853 Fukuyama-type congenital muscular dystrophy (fukutin) 
1554929_at KIAA0999 5,297695496 NA 
52159_at HEMK1 5,293319745 HemK methyltransferase family member 1 
224827_at DC-UbP 5,210263204 NA 
205641_s_at TRADD 5,19931747 TNFRSF1A-associated via death domain 
201295_s_at WSB1 5,191526754 WD repeat and SOCS box-containing 1 
218507_at HIG2 5,175505974 NA 
222386_s_at COPZ1 5,174500241 Coatomer protein complex, subunit zeta 1 
204057_at IRF8 5,165308859 Interferon regulatory factor 8 
218562_s_at TMEM57 5,163304991 Transmembrane protein 57 
221059_s_at CHST6 5,152533315 Carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 
209969_s_at STAT1 5,083186457 Signal transducer and activator of transcription 1, 91 kDa 
232027_at SYNE1 5,031819366 Spectrin repeat containing, nuclear envelope 1 
204633_s_at RPS6KA5 5,023419317 Ribosomal protein S6 kinase, 90 kDa, polypeptide 5 
216841_s_at SOD2 5,017952939 Superoxide dismutase 2, mitochondrial 
222691_at SLC35B3 5,009110445 Solute carrier family 35, member B3 
207700_s_at NCOA3 4,974277498 Nuclear receptor coactivator 3 
235574_at GBP4 4,96365421 Guanylate binding protein 4 
222045_s_at C20orf67 4,935840305 Chromosome 20 open reading frame 67 
204500_s_at AGTPBP1 4,934205697 ATP/GTP binding protein 1 
1556967_at ZDHHC14 4,92755238 Zinc finger, DHHC-type containing 14 
204613_at PLCG2 4,924269359 Phospholipase C, gamma 2 (phosphatidylinositol-specific) 
212378_at GART 4,924160286 Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 
210050_at TPI1 4,920823757 Triosephosphate isomerase 1 
204125_at NDUFAF1 4,920466452 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1 
204068_at STK3 4,894787293 Serine/threonine kinase 3 (STE20 homolog, yeast) 
201900_s_at AKR1A1 4,890038496 Aldo-keto reductase family 1, member A1 (aldehyde reductase) 
242939_at TFDP1 4,889767365 Transcription factor Dp-1 
226511_at MCART1 4,864612596 Mitochondrial carrier triple repeat 1 
201921_at LOC552891 4,824421802 NA 
223767_at GPR84 4,819947478 G protein-coupled receptor 84 
204565_at THEM2 4,79843566 Thioesterase superfamily member 2 
229398_at RAB18 4,788964099 RAB18, member RAS oncogene family 
227458_at C9orf46 4,769116802 Chromosome 9 open reading frame 46 
206584_at LY96 4,766515038 Lymphocyte antigen 96 
213246_at C14orf130 4,765949714 Chromosome 14 open reading frame 130 
213246_at C14orf130 4,765949714 Chromosome 14 open reading frame 130 
203518_at LYST 4,755336993 Lysosomal trafficking regulador 
236717_at LOC165186 4,713732588 NA 
226170_at EYA3 4,699440582 Eyes absent homolog 3 (Drosophila) 
212442_s_at LASS6 4,673946958 LAG1 longevity assurance homolog 6 (S. cerevisiae) 
227247_at PLEKHA8 4,640609475 Pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 
201463_s_at TALDO1 4,623771225 Transaldolase 1 
204702_s_at NFE2L3 4,608324388 Nuclear factor (erythroid-derived 2)-like 3 
224445_s_at ZFYVE21 4,60690338 Zinc finger, FYVE domain containing 21 
204446_s_at ALOX5 4,606635061 Arachidonate 5-lipoxygenase 
206478_at KIAA0125 4,604412442 KIAA0125 
215380_s_at C7orf24 4,59977998 Chromosome 7 open reading frame 24 
218230_at ARFIP1 4,584558778 ADP-ribosylation factor interacting protein 1 (arfaptin 1) 
229500_at SLC30A9 4,576485193 Solute carrier family 30 (zinc transporter), member 9 
209222_s_at OSBPL2 4,567763881 Oxysterol binding protein-like 2 
206267_s_at MATK 4,558282396 Megakaryocyte-associated tyrosine kinase 
214681_at GK 4,538965602 Glycerol kinase 
228106_at C4orf30 4,537274088 Chromosome 4 open reading frame 30 
218095_s_at TMEM165 4,527525331 Transmembrane protein 165 
212961_x_at CXorf40B 4,521246647 Chromosome X open reading frame 40B 
227438_at ALPK1 4,516024032 Alpha-kinase 1 
210347_s_at BCL11A 4,513152919 B-cell CLL/lymphoma 11A (zinc finger protein) 
206637_at P2RY14 4,513063383 Purinergic receptor P2Y, G-protein coupled, 14 
1561167_at ETV6 4,500052398 ets variant gene 6 (TEL oncogene) 
204254_s_at VDR 4,498636497 Vitamin D (1,25- dihydroxyvitamin D3) receptor 
206995_x_at SCARF1 4,491153208 Scavenger receptor class F, member 1 
201328_at ETS2 4,487520459 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) 
221843_s_at KIAA1609 4,485591378 KIAA1609 
207426_s_at TNFSF4 4,483796011 Tumor necrosis factor (ligand) superfamily, member 4 (tax-transcriptionally activated glycoprotein 1, 34 kDa) 
236995_x_at TFEC 4,482801297 Transcription factor EC 
209238_at STX3 4,468215629 Syntaxin 3 
40016_g_at MAST4 4,464348703 Microtubule associated serine/threonine kinase family member 4 
222357_at ZBTB20 4,452512078 Zinc finger and BTB domain containing 20 

NA indicates not applicable.

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