Table 3 Results of multivariate Cox... | American Society of Hematology

Table 3

Results of multivariate Cox regression analyses of OS and EFS in the validation cohort

Variable	Overall survival (n = 63)*		Event-free survival (n = 63)*
Variable	HR (95% CI)	P	HR (95% CI)	P
Age†	0.87 (0.66-1.13)	.30	0.94 (0.73-1.21)	.61
NPM1 mutation	0.43 (0.18-1.01)	.052	0.59 (0.27-1.31)	.20
FLT3 ITD	1.75 (0.63-4.81)	.28	2.08 (0.77-5.66)	.15
Microarray-based continuous risk score‡	3.40 (1.40-8.29)	.007	2.05 (0.90-4.66)	.09

Variable	Overall survival (n = 63)*		Event-free survival (n = 63)*
Variable	HR (95% CI)	P	HR (95% CI)	P
Age†	0.87 (0.66-1.13)	.30	0.94 (0.73-1.21)	.61
NPM1 mutation	0.43 (0.18-1.01)	.052	0.59 (0.27-1.31)	.20
FLT3 ITD	1.75 (0.63-4.81)	.28	2.08 (0.77-5.66)	.15
Microarray-based continuous risk score‡	3.40 (1.40-8.29)	.007	2.05 (0.90-4.66)	.09

One patient in the validation dataset was not included because of missing data on NPM1 mutational status.

The hazard ratio is given for an age difference of 10 years.

The hazard ratio is given for a change of the score equal to its interquartile range.