Table 3

Patient disposition and cytogenetic response

Cytogenetic responsenNotes
Overall CCgR 71
 
 
        Time to CCgR ≤ 12 months  69  
        Time to CCgR > 12 months   
    CML-unrelated death  Pulmonary embolism (1); NHL (1) 
    Stable CCgR 68   
    Loss of CCgR  CP 
Not CCgR 7  
    AE grade IV CP (detailed in text) 
    Loss of CHR CP 
    ABP Allogeneic BMT 
    No CgR < 6 months (100% Ph+ABP (2); CP (1) 
    PCgR at 12 months Allogeneic BMT 
Total 78  
Cytogenetic responsenNotes
Overall CCgR 71
 
 
        Time to CCgR ≤ 12 months  69  
        Time to CCgR > 12 months   
    CML-unrelated death  Pulmonary embolism (1); NHL (1) 
    Stable CCgR 68   
    Loss of CCgR  CP 
Not CCgR 7  
    AE grade IV CP (detailed in text) 
    Loss of CHR CP 
    ABP Allogeneic BMT 
    No CgR < 6 months (100% Ph+ABP (2); CP (1) 
    PCgR at 12 months Allogeneic BMT 
Total 78  

CCgR indicates complete cytogenetic response; CML, chronic myeloid leukemia; NHL, non-Hodgkin lymphoma; CP, chronic phase; AE, adverse event; CHR, complete hematologic response; ABP, accelerated or blastic phase; BMT, bone marrow transplantation; and PCgR, partial cytogenetic response. Bold values indicate totals.

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