Basic immunologic data
| . | P1* . | P2 . | Normal range . |
|---|---|---|---|
| T cells | |||
| CD3+/μL | 500-2050 | 475-1059 | 900-4500 |
| CD4+/μL | 250-828 | 105-273 | 500-2400 |
| CD8+/μL | 360-1860 | 133-272 | 300-1600 |
| % γ/δ + of CD3+ | 12 | 38-51 | <10 |
| % CD45RA+ of CD4+ | 4 | 7.0-8.9 | 50-86 |
| B cells | |||
| CD19+/CD20+/μL | 930-2400 | 257-676 | 200-2100 |
| NK cells | |||
| CD3−CD16+CD56+/μL | <10 | 12-22 | 100-1000 |
| Immunoglobulin | |||
| IgG, g/L | 1.9 | 4.97 | 5.0-13.6 |
| IgA, mg/L | < 100 | 1950 | 450-1350 |
| IgM, mg/L | 600 | 740 | 460-1900 |
| Specific IgG | t/d/p− | t/d/p/h/mu/me−; r+ | + |
| Proliferation, cpm × 10−3 | |||
| PHA | 3.3 ± 1.3 | 24.9 | > 53 |
| PWM | 5.0 ± 3.0 | 6.6 | > 20 |
| Tetanus | NA | 637 | >1000 |
| PPD | NA | 779 | >1000 |
| Candida | NA | 569 | >1000 |
| . | P1* . | P2 . | Normal range . |
|---|---|---|---|
| T cells | |||
| CD3+/μL | 500-2050 | 475-1059 | 900-4500 |
| CD4+/μL | 250-828 | 105-273 | 500-2400 |
| CD8+/μL | 360-1860 | 133-272 | 300-1600 |
| % γ/δ + of CD3+ | 12 | 38-51 | <10 |
| % CD45RA+ of CD4+ | 4 | 7.0-8.9 | 50-86 |
| B cells | |||
| CD19+/CD20+/μL | 930-2400 | 257-676 | 200-2100 |
| NK cells | |||
| CD3−CD16+CD56+/μL | <10 | 12-22 | 100-1000 |
| Immunoglobulin | |||
| IgG, g/L | 1.9 | 4.97 | 5.0-13.6 |
| IgA, mg/L | < 100 | 1950 | 450-1350 |
| IgM, mg/L | 600 | 740 | 460-1900 |
| Specific IgG | t/d/p− | t/d/p/h/mu/me−; r+ | + |
| Proliferation, cpm × 10−3 | |||
| PHA | 3.3 ± 1.3 | 24.9 | > 53 |
| PWM | 5.0 ± 3.0 | 6.6 | > 20 |
| Tetanus | NA | 637 | >1000 |
| PPD | NA | 779 | >1000 |
| Candida | NA | 569 | >1000 |
PWM indicates pokeweed mitogen; PPD, purified protein derivative of tuberculin; t, tetanus; d, diphtheria; p, pertussis; h, hepatitis b; mu, mumps; me, measles; r, rubella; and NA, not available.
Patient described by Stephan et al.10