Characterization of the ILK-deficient platelets
| Protein . | Level detected in the KO as a percentage of Ctrl . |
|---|---|
| α2 | 99.15 ± 7.62 |
| αIIb | 106.03 ± 16.25 |
| β1 | 86.72 ± 2.02* |
| β3 | 94.65 ± 4.38 |
| GPVI | 103.15 ± 8.20 |
| PINCH | 34.21 ± 10.30* |
| α-parvin | 61.36 ± 8.92* |
| Kindlin | 105 ± 5.54 |
| Talin | 86.54 ± 6.38 |
| Protein . | Level detected in the KO as a percentage of Ctrl . |
|---|---|
| α2 | 99.15 ± 7.62 |
| αIIb | 106.03 ± 16.25 |
| β1 | 86.72 ± 2.02* |
| β3 | 94.65 ± 4.38 |
| GPVI | 103.15 ± 8.20 |
| PINCH | 34.21 ± 10.30* |
| α-parvin | 61.36 ± 8.92* |
| Kindlin | 105 ± 5.54 |
| Talin | 86.54 ± 6.38 |
Relative levels of key adhesion receptors in the KO platelets compared to control were determined by immunoblotting. Densitometric data are expressed as a percentage of the control following adjustment for equivalent protein levels using GAPDH (35 kDa).
Mean plus or minus SEM, n = 3-8; *P ≤ .05.