Table 4

Univariate analysis of factors influencing AUC for T-cell subset immune reconstitution

FactorP (by 2-tailed t test between mean AUCs)
CD4+ T cells
CD8+ T cells
4 m6 m12 m4 m6 m12 m
Age (below median vs above) .02* .19 .05 .05 .13 .17 
Diagnosis (malignancy vs BMF) .76 .54 .56 .68 .70 .77 
CD34+ cell dose (above median vs not above) .59 .82 .47 .84 .71 .86 
CD4+ or CD8+ T-cell dose (above median vs not above) .32 .58 .74 .19 .08 .16 
aGvHD (grades B-D vs less than grade B) .26 .94 .39 .50 .54 .63 
CMV (reactivation vs no reactivation) .43 .64 .88 .08 .06 .005* 
FactorP (by 2-tailed t test between mean AUCs)
CD4+ T cells
CD8+ T cells
4 m6 m12 m4 m6 m12 m
Age (below median vs above) .02* .19 .05 .05 .13 .17 
Diagnosis (malignancy vs BMF) .76 .54 .56 .68 .70 .77 
CD34+ cell dose (above median vs not above) .59 .82 .47 .84 .71 .86 
CD4+ or CD8+ T-cell dose (above median vs not above) .32 .58 .74 .19 .08 .16 
aGvHD (grades B-D vs less than grade B) .26 .94 .39 .50 .54 .63 
CMV (reactivation vs no reactivation) .43 .64 .88 .08 .06 .005* 

AUC indicates area under curve; other abbreviations as in Table 1.

*

Statistically significant.

Grade B-D aGVHD (n = 3) versus less than grade B aGVHD (n = 5).

CMV reactivation (n = 3) versus no CMV reactivation (n = 5).

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