Table 1 Clinical and biologic... | American Society of Hematology

Table 1

Clinical and biologic characteristics of the MM patients

MM patient no.	Age, y	Patient stage	BM plasma cells, %	State of disease	PD/ATO in vitro treatment
1	66	IIIa	65	New diagnosis	+
2	57	IIIa	90	Relapse	+
3	74	IIIa	70	Relapse	+
4	76	IIa	90	New diagnosis	−
5	64	IIIa	58	Relapse	+
6	65	IIIa	50	New diagnosis	+
7	61	IIIa	70	Relapse	+
8	89	Ia	30	New diagnosis	−
9	36	Ia	20	New diagnosis	−
10	60	IIa	60	New diagnosis	+
11	70	IIIa	28	New diagnosis	+
12	49	IIIa	80	New diagnosis	+

MM patient no.	Age, y	Patient stage	BM plasma cells, %	State of disease	PD/ATO in vitro treatment
1	66	IIIa	65	New diagnosis	+
2	57	IIIa	90	Relapse	+
3	74	IIIa	70	Relapse	+
4	76	IIa	90	New diagnosis	−
5	64	IIIa	58	Relapse	+
6	65	IIIa	50	New diagnosis	+
7	61	IIIa	70	Relapse	+
8	89	Ia	30	New diagnosis	−
9	36	Ia	20	New diagnosis	−
10	60	IIa	60	New diagnosis	+
11	70	IIIa	28	New diagnosis	+
12	49	IIIa	80	New diagnosis	+

Primary CD 138⁺ MM cells were isolated from BM aspiration of MM patients at the diagnosis or relapse and were treated in vitro with PD 184352 (1 μM) and/or ATO (2 μM) for 24 to 48 hours.

+ indicates responder; and −, nonresponder.

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