Odds ratios for venous thrombosis for combinations of risk factors
| . | FII . | FVIII . | FVL* . | OC* . | BMI* . | Fam† . |
|---|---|---|---|---|---|---|
| FII | 2.2 (1.3-3.7) | |||||
| FVIII | 7.9 (3.4-18.3) | 6.2 (3.6-10.5) | ||||
| FVL | 17.5 (2.3-135) | 24.7 (4.4-139) | 4.5 (1.9-10.4) | |||
| OC | 4.6 (1.1-19.8) | 51.7 (5.4-498) | 18.3 (2.0-171) | 5.0 (2.1-12.1) | ||
| BMI | 9.5 (3.6-25.1) | 18.6 (7.0-49.9) | 20.5 (2.5-170) | 31.4 (3.0-334) | 1.9 (1.4-2.7) | |
| Fam† | 2.4 (0.9-6.1) | 8.7 (3.5-21.7) | 4.7 (1.7-16.5) | 10.7 (1.5-75.6) | 2.4 (1.0-5.8) | 1.7 (1.0-2.9) |
| . | FII . | FVIII . | FVL* . | OC* . | BMI* . | Fam† . |
|---|---|---|---|---|---|---|
| FII | 2.2 (1.3-3.7) | |||||
| FVIII | 7.9 (3.4-18.3) | 6.2 (3.6-10.5) | ||||
| FVL | 17.5 (2.3-135) | 24.7 (4.4-139) | 4.5 (1.9-10.4) | |||
| OC | 4.6 (1.1-19.8) | 51.7 (5.4-498) | 18.3 (2.0-171) | 5.0 (2.1-12.1) | ||
| BMI | 9.5 (3.6-25.1) | 18.6 (7.0-49.9) | 20.5 (2.5-170) | 31.4 (3.0-334) | 1.9 (1.4-2.7) | |
| Fam† | 2.4 (0.9-6.1) | 8.7 (3.5-21.7) | 4.7 (1.7-16.5) | 10.7 (1.5-75.6) | 2.4 (1.0-5.8) | 1.7 (1.0-2.9) |
FVL indicates factor V Leiden mutation; OC, oral contraceptive use; BMI, body mass index > 26.9 kg/m2 as compared to a BMI of <23.7 kg/m2. For each combination, the odds ratio for presence of both risk factors compared to absence of both factors is presented. In the boxes where the risk factor in the column is the same as in the row, the odds ratio for presence of only that risk factor is given.
Fam indicates a positive family history, meaning at least one thrombotic event in a brother, sister, or parent.