Patient characteristics
| Patient characteristic . | All patients (N = 199) . | Unpaired patients (n = 76) . | P* . | ||
|---|---|---|---|---|---|
| n . | % . | n . | % . | ||
| Median age, y (range) | 38 | (15-83) | 44 | (16-77) | .23 |
| Male sex | 122 | 61 | 38 | 50 | .37 |
| Median percentage of marrow blasts (range) | 86 | (1-99) | 87 | (2-97) | .44 |
| Median WBC, ×109/L (range) | 6.0 | (0.3-602.5) | 4.5 | (0.7-372.6) | .06 |
| Median Hgb, g/dL (range) | 8.8 | (2.5-16.3) | 8.85 | (4-15.8) | .82 |
| Median platelet count, ×109/L (range) | 53 | (10-529) | 53.5 | (10-348) | .95 |
| Cytogenetics | |||||
| Diploid | 64 | 32 | 21 | 28 | .07 |
| Other | 89 | 45 | 35 | 46 | |
| IM | 42 | 21 | 16 | 21 | |
| ND | 4 | 2 | 4 | 5 | |
| Relapse | 105 | 53 | 36 | 47 | .31 |
| Disease-free survival, wk, median (range) | 136 | (112-NR) | 208 | (110-NR) | .21 |
| Overall survival, wk, median (range) | 209 | (135-NR) | 234 | (179-NR) | .39 |
| Patient characteristic . | All patients (N = 199) . | Unpaired patients (n = 76) . | P* . | ||
|---|---|---|---|---|---|
| n . | % . | n . | % . | ||
| Median age, y (range) | 38 | (15-83) | 44 | (16-77) | .23 |
| Male sex | 122 | 61 | 38 | 50 | .37 |
| Median percentage of marrow blasts (range) | 86 | (1-99) | 87 | (2-97) | .44 |
| Median WBC, ×109/L (range) | 6.0 | (0.3-602.5) | 4.5 | (0.7-372.6) | .06 |
| Median Hgb, g/dL (range) | 8.8 | (2.5-16.3) | 8.85 | (4-15.8) | .82 |
| Median platelet count, ×109/L (range) | 53 | (10-529) | 53.5 | (10-348) | .95 |
| Cytogenetics | |||||
| Diploid | 64 | 32 | 21 | 28 | .07 |
| Other | 89 | 45 | 35 | 46 | |
| IM | 42 | 21 | 16 | 21 | |
| ND | 4 | 2 | 4 | 5 | |
| Relapse | 105 | 53 | 36 | 47 | .31 |
| Disease-free survival, wk, median (range) | 136 | (112-NR) | 208 | (110-NR) | .21 |
| Overall survival, wk, median (range) | 209 | (135-NR) | 234 | (179-NR) | .39 |
WBC indicates white blood cells; Hgb, hemoglobin; IM, insufficient metaphases; ND, not done; and NR, not reached.
This analysis was performed between the 76 patients without a paired diagnostic sample (n = 76) and those with a paired sample (n = 123). Thus, results are shown for the full cohort of patients (N = 199), as they are the focus of this analysis.