Comparison of planned cumulative drug doses during induction
| . | CCG 1882 . | CALGB . |
|---|---|---|
| Prednisone, mg/m2 | 1680 | 1260 |
| Vincristine, mg | 8 | 8 |
| l-Asparaginase, U/m2 | 54 000 | 36 000 |
| Daunorubicin, mg/m2 | 100 | 135-240* |
| Cyclophosphamide, mg/m2 | 1200 | |
| IT-methotrexate, d | 14 | |
| IT-cytarabine, d | 0 |
| . | CCG 1882 . | CALGB . |
|---|---|---|
| Prednisone, mg/m2 | 1680 | 1260 |
| Vincristine, mg | 8 | 8 |
| l-Asparaginase, U/m2 | 54 000 | 36 000 |
| Daunorubicin, mg/m2 | 100 | 135-240* |
| Cyclophosphamide, mg/m2 | 1200 | |
| IT-methotrexate, d | 14 | |
| IT-cytarabine, d | 0 |
*In CALGB 19802, all patients younger than 60 years received daunorubicin at 80 mg/m2 per day for 3 days.