Additional cytogenetic abnormalities among patients with CBF
| Additional cytogenetic abnormalities . | t(8;21), no. . | inv(16), no. . |
|---|---|---|
| None | 206 | 69 |
| With additional abnormalities | 49 | 14* |
| −Y | 10 | 0 |
| −X | 5 | 0 |
| Trisomy 22 | 0 | 3† |
| Trisomy 8 | 0 | 2† |
| Trisomy 4 | 2* | 0 |
| Complex | 7 | 4 |
| del(7q) | 1† | 2 |
| del(9q) | 6 | 0 |
| Other abnormalities | 27 | 9‡ |
| Unknown | 7 | 1 |
| Additional cytogenetic abnormalities . | t(8;21), no. . | inv(16), no. . |
|---|---|---|
| None | 206 | 69 |
| With additional abnormalities | 49 | 14* |
| −Y | 10 | 0 |
| −X | 5 | 0 |
| Trisomy 22 | 0 | 3† |
| Trisomy 8 | 0 | 2† |
| Trisomy 4 | 2* | 0 |
| Complex | 7 | 4 |
| del(7q) | 1† | 2 |
| del(9q) | 6 | 0 |
| Other abnormalities | 27 | 9‡ |
| Unknown | 7 | 1 |
Patients with additional change to inv(16) and trisomy 4 with t(8;21) tended to show poor survival tendency, with P < .1.
All patients with trisomy 22, trisomy 8 with inv(16), and del(7q) with t(8;21) were alive and censored at survival analysis.
Other abnormalities with inv(16) was poorly prognostic, with P < .001.