Patient demographics
| . | Donor KIR genotype . | P* . | |
|---|---|---|---|
| Genotype A/A, n = 131 (29%) . | Genotype B/x, n = 317 (71%) . | ||
| Median age, y (range) | 34.1 (1.8-58.4) | 33.3 (0.8-60.8) | .57 |
| Disease status (%) | .53 | ||
| Early | 25 (19.1) | 61 (19.2) | |
| Intermediate | 42 (32.1) | 118 (37.2) | |
| Advanced | 64 (48.9) | 138 (43.5) | |
| Donor: recipient HLA-allele matching at A, B, C, DRB1, and DQB1 (%) | .01 | ||
| 10/10 allele matched | 51 (38.9) | 158 (49.8) | |
| 9/10 | 28 (21.4) | 67 (21.1) | |
| 8/10 | 39 (29.8) | 51 (16.1) | |
| 7/10 | 13 (9.9) | 41 (12.9) | |
| HLA match group (%) | .10 | ||
| HLA 10/10 allele matched | 51 (38.9) | 158 (49.8) | |
| HLA mismatched KIR-ligand matched | 58 (44.3) | 111 (35.0) | |
| HLA mismatched KIR-ligand mismatched | 22 (16.8) | 48 (15.1) | |
| Sex match, donor/recipient (%) | .33 | ||
| Male/male | 40 (30.5) | 117 (36.9) | |
| Male/female | 32 (24.4) | 85 (26.8) | |
| Female/male | 24 (18.3) | 52 (16.4) | |
| Female/female | 35 (26.7) | 63 (19.9) | |
| CMV serostatus (%) | .62 | ||
| Donor −/recipient − | 40 (30.5) | 106 (33.4) | |
| Donor +/recipient − | 17 (13.0) | 47 (14.8) | |
| Donor any/recipient + | 73 (55.7) | 160 (50.5) | |
| Missing | 1 (0.8) | 4 (1.3) | |
| Graft type (%) | .89 | ||
| Bone marrow | 116 (88.5) | 281 (88.6) | |
| Peripheral blood progenitor cells | 15 (11.5) | 36 (11.4) | |
| Karnofsky score (%) | .08 | ||
| 90 to 100 | 77 (58.8) | 196 (61.8) | |
| 10 to 80 | 52 (39.7) | 103 (32.5) | |
| Unknown | 2 (1.5) | 18 (5.7) | |
| Median time from diagnosis to transplantation y (range) | 1.1 (0.0-4.0) | 1.2 (0.0-8.2) | .46 |
| Race (%) | .91 | ||
| White | 117 (89.3) | 286 (90.2) | |
| Nonwhite | 14 (10.7) | 31 (10.8) | |
| . | Donor KIR genotype . | P* . | |
|---|---|---|---|
| Genotype A/A, n = 131 (29%) . | Genotype B/x, n = 317 (71%) . | ||
| Median age, y (range) | 34.1 (1.8-58.4) | 33.3 (0.8-60.8) | .57 |
| Disease status (%) | .53 | ||
| Early | 25 (19.1) | 61 (19.2) | |
| Intermediate | 42 (32.1) | 118 (37.2) | |
| Advanced | 64 (48.9) | 138 (43.5) | |
| Donor: recipient HLA-allele matching at A, B, C, DRB1, and DQB1 (%) | .01 | ||
| 10/10 allele matched | 51 (38.9) | 158 (49.8) | |
| 9/10 | 28 (21.4) | 67 (21.1) | |
| 8/10 | 39 (29.8) | 51 (16.1) | |
| 7/10 | 13 (9.9) | 41 (12.9) | |
| HLA match group (%) | .10 | ||
| HLA 10/10 allele matched | 51 (38.9) | 158 (49.8) | |
| HLA mismatched KIR-ligand matched | 58 (44.3) | 111 (35.0) | |
| HLA mismatched KIR-ligand mismatched | 22 (16.8) | 48 (15.1) | |
| Sex match, donor/recipient (%) | .33 | ||
| Male/male | 40 (30.5) | 117 (36.9) | |
| Male/female | 32 (24.4) | 85 (26.8) | |
| Female/male | 24 (18.3) | 52 (16.4) | |
| Female/female | 35 (26.7) | 63 (19.9) | |
| CMV serostatus (%) | .62 | ||
| Donor −/recipient − | 40 (30.5) | 106 (33.4) | |
| Donor +/recipient − | 17 (13.0) | 47 (14.8) | |
| Donor any/recipient + | 73 (55.7) | 160 (50.5) | |
| Missing | 1 (0.8) | 4 (1.3) | |
| Graft type (%) | .89 | ||
| Bone marrow | 116 (88.5) | 281 (88.6) | |
| Peripheral blood progenitor cells | 15 (11.5) | 36 (11.4) | |
| Karnofsky score (%) | .08 | ||
| 90 to 100 | 77 (58.8) | 196 (61.8) | |
| 10 to 80 | 52 (39.7) | 103 (32.5) | |
| Unknown | 2 (1.5) | 18 (5.7) | |
| Median time from diagnosis to transplantation y (range) | 1.1 (0.0-4.0) | 1.2 (0.0-8.2) | .46 |
| Race (%) | .91 | ||
| White | 117 (89.3) | 286 (90.2) | |
| Nonwhite | 14 (10.7) | 31 (10.8) | |
P values from Welch t test or a χ2 test.