Table 2

Relapse-free survival after URD HCT: multivariate analysis

All samplesRR of relapse or death95% CIP
KIR genotype    
    B/x (compared with A/A) 0.70 0.55-0.88 .002 
Transplant group    
    HLA mismatched/KIR-ligand match (compared with 10/10 HLA matched) 1.21 0.95-1.54 .13 
    HLA mismatched/KIR-ligand mismatch (compared with10/10 HLA matched) 1.65 1.22-2.23 .001 
Disease status    
    Intermediate (compared with early) 1.41 0.99-2.02 .06 
    Advanced (compared with early) 2.17 1.58-2.99 <.001 
Age (categoric)   .03 
Karnofsky performance status   .01 
Time from diagnosis to transplantation, per year 0.88 0.77-1.02 .08 
Nonwhite 1.34 0.95-1.88 .10 
All samplesRR of relapse or death95% CIP
KIR genotype    
    B/x (compared with A/A) 0.70 0.55-0.88 .002 
Transplant group    
    HLA mismatched/KIR-ligand match (compared with 10/10 HLA matched) 1.21 0.95-1.54 .13 
    HLA mismatched/KIR-ligand mismatch (compared with10/10 HLA matched) 1.65 1.22-2.23 .001 
Disease status    
    Intermediate (compared with early) 1.41 0.99-2.02 .06 
    Advanced (compared with early) 2.17 1.58-2.99 <.001 
Age (categoric)   .03 
Karnofsky performance status   .01 
Time from diagnosis to transplantation, per year 0.88 0.77-1.02 .08 
Nonwhite 1.34 0.95-1.88 .10 

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