Hematology and hemostasis in Orai1−/− chimeras
| . | Orai1+/+ . | Orai1−/− . |
|---|---|---|
| Platelets | 8036 ± 215 | 8888 ± 153 |
| MPV, fL | 5.27 ± 0.12 | 5.35 ± 0.19 |
| Erythrocytes | 9150 ± 198 | 8718 ± 291 |
| HCT, % | 45.9 ± 0.99 | 42.6 ± 1.2 |
| aPTT, s | 38.7 ± 6.8 | 37.7 ± 2.9 |
| QT, % | 9.4 ± 0.5 | 9.8 ± 0.7 |
| INR | 0.88 ± 0.08 | 0.83 ± 0.04 |
| . | Orai1+/+ . | Orai1−/− . |
|---|---|---|
| Platelets | 8036 ± 215 | 8888 ± 153 |
| MPV, fL | 5.27 ± 0.12 | 5.35 ± 0.19 |
| Erythrocytes | 9150 ± 198 | 8718 ± 291 |
| HCT, % | 45.9 ± 0.99 | 42.6 ± 1.2 |
| aPTT, s | 38.7 ± 6.8 | 37.7 ± 2.9 |
| QT, % | 9.4 ± 0.5 | 9.8 ± 0.7 |
| INR | 0.88 ± 0.08 | 0.83 ± 0.04 |
Platelet and erythrocyte counts per nanoliter and coagulation parameters for control and Orai1−/− chimeras. Values given are mean values plus or minus SD of 5 mice for each genotype.
MPV indicates mean platelet volume; HCT, hematocrit; aPTT, activated partial thromboplastin time; QT, quick test; and INR, international normalized ratio.