WHO classification of myeloid neoplasms and acute leukemia
| Myeloproliferative neoplasms (MPN) |
| Chronic myelogenous leukemia, BCR-ABL1–positive |
| Chronic neutrophilic leukemia |
| Polycythemia vera |
| Primary myelofibrosis |
| Essential thrombocythemia |
| Chronic eosinophilic leukemia, not otherwise specified |
| Mastocytosis |
| Myeloproliferative neoplasms, unclassifiable |
| Myeloid and lymphoid neoplasms associated with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1 |
| Myeloid and lymphoid neoplasms associated with PDGFRA rearrangement |
| Myeloid neoplasms associated with PDGFRB rearrangement |
| Myeloid and lymphoid neoplasms associated with FGFR1 abnormalities |
| Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) |
| Chronic myelomonocytic leukemia |
| Atypical chronic myeloid leukemia, BCR-ABL1–negative |
| Juvenile myelomonocytic leukemia |
| Myelodysplastic/myeloproliferative neoplasm, unclassifiable |
| Provisional entity: refractory anemia with ring sideroblasts and thrombocytosis |
| Myelodysplastic syndrome (MDS) |
| Refractory cytopenia with unilineage dysplasia |
| Refractory anemia |
| Refractory neutropenia |
| Refractory thrombocytopenia |
| Refractory anemia with ring sideroblasts |
| Refractory cytopenia with multilineage dysplasia |
| Refractory anemia with excess blasts |
| Myelodysplastic syndrome with isolated del(5q) |
| Myelodysplastic syndrome, unclassifiable |
| Childhood myelodysplastic syndrome |
| Provisional entity: refractory cytopenia of childhood |
| Acute myeloid leukemia and related neoplasms |
| Acute myeloid leukemia with recurrent genetic abnormalities |
| AML with t(8;21)(q22;q22); RUNX1-RUNX1T1 |
| AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11 |
| APL with t(15;17)(q22;q12); PML-RARA |
| AML with t(9;11)(p22;q23); MLLT3-MLL |
| AML with t(6;9)(p23;q34); DEK-NUP214 |
| AML with inv(3)(q21q26.2) or t(3;3)(q21;q26.2); RPN1-EVI1 |
| AML (megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1 |
| Provisional entity: AML with mutated NPM1 |
| Provisional entity: AML with mutated CEBPA |
| Acute myeloid leukemia with myelodysplasia-related changes |
| Therapy-related myeloid neoplasms |
| Acute myeloid leukemia, not otherwise specified |
| AML with minimal differentiation |
| AML without maturation |
| AML with maturation |
| Acute myelomonocytic leukemia |
| Acute monoblastic/monocytic leukemia |
| Acute erythroid leukemia |
| Pure erythroid leukemia |
| Erythroleukemia, erythroid/myeloid |
| Acute megakaryoblastic leukemia |
| Acute basophilic leukemia |
| Acute panmyelosis with myelofibrosis |
| Myeloid sarcoma |
| Myeloid proliferations related to Down syndrome |
| Transient abnormal myelopoiesis |
| Myeloid leukemia associated with Down syndrome |
| Blastic plasmacytoid dendritic cell neoplasm |
| Acute leukemias of ambiguous lineage |
| Acute undifferentiated leukemia |
| Mixed phenotype acute leukemia with t(9;22)(q34;q11.2); BCR-ABL1 |
| Mixed phenotype acute leukemia with t(v;11q23); MLL rearranged |
| Mixed phenotype acute leukemia, B-myeloid, NOS |
| Mixed phenotype acute leukemia, T-myeloid, NOS |
| Provisional entity: natural killer (NK) cell lymphoblastic leukemia/lymphoma |
| B lymphoblastic leukemia/lymphoma |
| B lymphoblastic leukemia/lymphoma, NOS |
| B lymphoblastic leukemia/lymphoma with recurrent genetic abnormalities |
| B lymphoblastic leukemia/lymphoma with t(9;22)(q34;q11.2);BCR-ABL 1 |
| B lymphoblastic leukemia/lymphoma with t(v;11q23);MLL rearranged |
| B lymphoblastic leukemia/lymphoma with t(12;21)(p13;q22) TEL-AML1 (ETV6-RUNX1) |
| B lymphoblastic leukemia/lymphoma with hyperdiploidy |
| B lymphoblastic leukemia/lymphoma with hypodiploidy |
| B lymphoblastic leukemia/lymphoma with t(5;14)(q31;q32) IL3-IGH |
| B lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3);TCF3-PBX1 |
| T lymphoblastic leukemia/lymphoma |
| Myeloproliferative neoplasms (MPN) |
| Chronic myelogenous leukemia, BCR-ABL1–positive |
| Chronic neutrophilic leukemia |
| Polycythemia vera |
| Primary myelofibrosis |
| Essential thrombocythemia |
| Chronic eosinophilic leukemia, not otherwise specified |
| Mastocytosis |
| Myeloproliferative neoplasms, unclassifiable |
| Myeloid and lymphoid neoplasms associated with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1 |
| Myeloid and lymphoid neoplasms associated with PDGFRA rearrangement |
| Myeloid neoplasms associated with PDGFRB rearrangement |
| Myeloid and lymphoid neoplasms associated with FGFR1 abnormalities |
| Myelodysplastic/myeloproliferative neoplasms (MDS/MPN) |
| Chronic myelomonocytic leukemia |
| Atypical chronic myeloid leukemia, BCR-ABL1–negative |
| Juvenile myelomonocytic leukemia |
| Myelodysplastic/myeloproliferative neoplasm, unclassifiable |
| Provisional entity: refractory anemia with ring sideroblasts and thrombocytosis |
| Myelodysplastic syndrome (MDS) |
| Refractory cytopenia with unilineage dysplasia |
| Refractory anemia |
| Refractory neutropenia |
| Refractory thrombocytopenia |
| Refractory anemia with ring sideroblasts |
| Refractory cytopenia with multilineage dysplasia |
| Refractory anemia with excess blasts |
| Myelodysplastic syndrome with isolated del(5q) |
| Myelodysplastic syndrome, unclassifiable |
| Childhood myelodysplastic syndrome |
| Provisional entity: refractory cytopenia of childhood |
| Acute myeloid leukemia and related neoplasms |
| Acute myeloid leukemia with recurrent genetic abnormalities |
| AML with t(8;21)(q22;q22); RUNX1-RUNX1T1 |
| AML with inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11 |
| APL with t(15;17)(q22;q12); PML-RARA |
| AML with t(9;11)(p22;q23); MLLT3-MLL |
| AML with t(6;9)(p23;q34); DEK-NUP214 |
| AML with inv(3)(q21q26.2) or t(3;3)(q21;q26.2); RPN1-EVI1 |
| AML (megakaryoblastic) with t(1;22)(p13;q13); RBM15-MKL1 |
| Provisional entity: AML with mutated NPM1 |
| Provisional entity: AML with mutated CEBPA |
| Acute myeloid leukemia with myelodysplasia-related changes |
| Therapy-related myeloid neoplasms |
| Acute myeloid leukemia, not otherwise specified |
| AML with minimal differentiation |
| AML without maturation |
| AML with maturation |
| Acute myelomonocytic leukemia |
| Acute monoblastic/monocytic leukemia |
| Acute erythroid leukemia |
| Pure erythroid leukemia |
| Erythroleukemia, erythroid/myeloid |
| Acute megakaryoblastic leukemia |
| Acute basophilic leukemia |
| Acute panmyelosis with myelofibrosis |
| Myeloid sarcoma |
| Myeloid proliferations related to Down syndrome |
| Transient abnormal myelopoiesis |
| Myeloid leukemia associated with Down syndrome |
| Blastic plasmacytoid dendritic cell neoplasm |
| Acute leukemias of ambiguous lineage |
| Acute undifferentiated leukemia |
| Mixed phenotype acute leukemia with t(9;22)(q34;q11.2); BCR-ABL1 |
| Mixed phenotype acute leukemia with t(v;11q23); MLL rearranged |
| Mixed phenotype acute leukemia, B-myeloid, NOS |
| Mixed phenotype acute leukemia, T-myeloid, NOS |
| Provisional entity: natural killer (NK) cell lymphoblastic leukemia/lymphoma |
| B lymphoblastic leukemia/lymphoma |
| B lymphoblastic leukemia/lymphoma, NOS |
| B lymphoblastic leukemia/lymphoma with recurrent genetic abnormalities |
| B lymphoblastic leukemia/lymphoma with t(9;22)(q34;q11.2);BCR-ABL 1 |
| B lymphoblastic leukemia/lymphoma with t(v;11q23);MLL rearranged |
| B lymphoblastic leukemia/lymphoma with t(12;21)(p13;q22) TEL-AML1 (ETV6-RUNX1) |
| B lymphoblastic leukemia/lymphoma with hyperdiploidy |
| B lymphoblastic leukemia/lymphoma with hypodiploidy |
| B lymphoblastic leukemia/lymphoma with t(5;14)(q31;q32) IL3-IGH |
| B lymphoblastic leukemia/lymphoma with t(1;19)(q23;p13.3);TCF3-PBX1 |
| T lymphoblastic leukemia/lymphoma |