Clinical characteristics of MDS data
| . | N164, n (%) . | N139, n (%) . | N110, n (%) . |
|---|---|---|---|
| Age at diagnosis, y | |||
| Younger than 50 | 8 (5) | 7 (5) | 6 (5) |
| 51-60 | 21 (13) | 19 (14) | 17 (15) |
| 61-70 | 30 (18) | 25 (18) | 19 (17) |
| 71-80 | 50 (30) | 43 (31) | 35 (32) |
| Older than 81 | 52 (32) | 42 (30) | 33 (30) |
| Unknown | 3 (2) | 3 (2) | 0 (0) |
| Sex | |||
| Male | 66 (40) | 55 (40) | 47 (43) |
| Female | 98 (60) | 84 (60) | 63 (57) |
| Disease classification | |||
| 5q− syndrome | 11 (7) | 11 (8) | 10 (9) |
| CMML | 25 (15) | ||
| RA | 39 (24) | 39 (28) | 35 (32) |
| RAEB1 | 26 (16) | 26 (19) | 19 (17) |
| RAEB2 | 22 (13) | 22 (16) | 19 (17) |
| RARS | 29 (18) | 29 (21) | 20 (18) |
| RCMD | 12 (7) | 12 (9) | 7 (6) |
| IPSS scores | |||
| Low | 72 (44) | 59 (42) | 53 (48) |
| Intermediate-1 | 62 (38) | 51 (37) | 33 (30) |
| Intermediate-2 | 25 (15) | 24 (17) | 19 (17) |
| High | 5 (3) | 5 (4) | 5 (5) |
| DC model classification | |||
| AML | 37 (23) | 31 (22) | 25 (23) |
| MDS | 82 (50) | 70 (50) | 55 (50) |
| “None-of-the-targets” | 39 (24) | 34 (24) | 27 (25) |
| Tied between class calls | 6 (4) | 4 (3) | 3 (3) |
| Blast cell count | |||
| Less than 5% | 114 (70) | 92 (66) | 72 (65) |
| 5%-10% | 29 (18) | 26 (19) | 20 (18) |
| 11%-20% | 21 (13) | 21 (15) | 18 (16) |
| Cytogenetics | |||
| Normal | 117 (71) | 97 (70) | 78 (71) |
| Good (1 of: del(5q), del(20q), −Y) | 18 (11) | 18 (13) | 15 (14) |
| Intermediate (any abnormalities) | 19 (12) | 14 (10) | 12 (11) |
| Poor (complex: > 3 abnormalities) | 8 (5) | 8 (6) | 4 (4) |
| Poor (chromosome 7 abnormalities) | 2 (1) | 2 (1) | 1 (1) |
| Cytopenia | |||
| 0 or 1 cytopenias | 98 (60) | 79 (57) | 65 (59) |
| 2 or 3 cytopenias | 66 (40) | 60 (43) | 45 (41) |
| . | N164, n (%) . | N139, n (%) . | N110, n (%) . |
|---|---|---|---|
| Age at diagnosis, y | |||
| Younger than 50 | 8 (5) | 7 (5) | 6 (5) |
| 51-60 | 21 (13) | 19 (14) | 17 (15) |
| 61-70 | 30 (18) | 25 (18) | 19 (17) |
| 71-80 | 50 (30) | 43 (31) | 35 (32) |
| Older than 81 | 52 (32) | 42 (30) | 33 (30) |
| Unknown | 3 (2) | 3 (2) | 0 (0) |
| Sex | |||
| Male | 66 (40) | 55 (40) | 47 (43) |
| Female | 98 (60) | 84 (60) | 63 (57) |
| Disease classification | |||
| 5q− syndrome | 11 (7) | 11 (8) | 10 (9) |
| CMML | 25 (15) | ||
| RA | 39 (24) | 39 (28) | 35 (32) |
| RAEB1 | 26 (16) | 26 (19) | 19 (17) |
| RAEB2 | 22 (13) | 22 (16) | 19 (17) |
| RARS | 29 (18) | 29 (21) | 20 (18) |
| RCMD | 12 (7) | 12 (9) | 7 (6) |
| IPSS scores | |||
| Low | 72 (44) | 59 (42) | 53 (48) |
| Intermediate-1 | 62 (38) | 51 (37) | 33 (30) |
| Intermediate-2 | 25 (15) | 24 (17) | 19 (17) |
| High | 5 (3) | 5 (4) | 5 (5) |
| DC model classification | |||
| AML | 37 (23) | 31 (22) | 25 (23) |
| MDS | 82 (50) | 70 (50) | 55 (50) |
| “None-of-the-targets” | 39 (24) | 34 (24) | 27 (25) |
| Tied between class calls | 6 (4) | 4 (3) | 3 (3) |
| Blast cell count | |||
| Less than 5% | 114 (70) | 92 (66) | 72 (65) |
| 5%-10% | 29 (18) | 26 (19) | 20 (18) |
| 11%-20% | 21 (13) | 21 (15) | 18 (16) |
| Cytogenetics | |||
| Normal | 117 (71) | 97 (70) | 78 (71) |
| Good (1 of: del(5q), del(20q), −Y) | 18 (11) | 18 (13) | 15 (14) |
| Intermediate (any abnormalities) | 19 (12) | 14 (10) | 12 (11) |
| Poor (complex: > 3 abnormalities) | 8 (5) | 8 (6) | 4 (4) |
| Poor (chromosome 7 abnormalities) | 2 (1) | 2 (1) | 1 (1) |
| Cytopenia | |||
| 0 or 1 cytopenias | 98 (60) | 79 (57) | 65 (59) |
| 2 or 3 cytopenias | 66 (40) | 60 (43) | 45 (41) |