Table 2 Post–G-CSF peripheral blood CD... | American Society of Hematology

Table 2

Post–G-CSF peripheral blood CD 34⁺ cell counts and CD 34⁺ apheresis yields according to G-CSF dose (μg/kg) and ethnicity

Administered G-CSF dose, μg/kg*	All donors	White	Black	Hispanic	Asian/Pacific
10 μg/kg
N	561	350	67	108	36
Male, %	51%	51%	50%	50%	52%
Weight, kg	78 ± 17	79 ± 17	81 ± 16	76 ± 17	68 ± 16
Total G-CSF received, μg/d	788 ± 169	801 ± 169	815 ± 152	766 ± 169	688 ± 160
CD34⁺ response
Peripheral blood, per μL	84 ± 51†	77 ± 45	102 ± 59	93 ± 49	101 ± 74
Yield, 10⁶/L processed	32 ± 20‡	30 ± 19	40 ± 26	33 ± 20	36 ± 24
16 μg/kg
N	27	21	2	4	0
Male, %	37%	38%	0%	50%	—
Weight, kg	78 ± 15	78 ± 16	82 ± 10	74 ± 10	—
Total G-CSF received, μg/d	1247 ± 236	1253 ± 255	1335 ± 191	1170 ± 159	—
CD34⁺ response					—
Peripheral blood, per μL	119 ± 49†	114 ± 52	144 ± 26	130 ± 40	—
Yield, 10⁶/L processed	39 ± 17‡	38 ± 18	46 ± 15	41 ± 17	—

Administered G-CSF dose, μg/kg*	All donors	White	Black	Hispanic	Asian/Pacific
10 μg/kg
N	561	350	67	108	36
Male, %	51%	51%	50%	50%	52%
Weight, kg	78 ± 17	79 ± 17	81 ± 16	76 ± 17	68 ± 16
Total G-CSF received, μg/d	788 ± 169	801 ± 169	815 ± 152	766 ± 169	688 ± 160
CD34⁺ response
Peripheral blood, per μL	84 ± 51†	77 ± 45	102 ± 59	93 ± 49	101 ± 74
Yield, 10⁶/L processed	32 ± 20‡	30 ± 19	40 ± 26	33 ± 20	36 ± 24
16 μg/kg
N	27	21	2	4	0
Male, %	37%	38%	0%	50%	—
Weight, kg	78 ± 15	78 ± 16	82 ± 10	74 ± 10	—
Total G-CSF received, μg/d	1247 ± 236	1253 ± 255	1335 ± 191	1170 ± 159	—
CD34⁺ response					—
Peripheral blood, per μL	119 ± 49†	114 ± 52	144 ± 26	130 ± 40	—
Yield, 10⁶/L processed	39 ± 17‡	38 ± 18	46 ± 15	41 ± 17	—

—, not applicable.

Includes donors with actual G-CSF received within 10% of prescribed dose of 10 or 16 μg/kg per day.

P < .001, 16 versus 10 μg/kg per day G-CSF for peripheral blood CD34⁺ cell count.

P = .02, 16 versus 10 μg/kg per day G-CSF for CD34⁺ apheresis yields per L processed.