Adverse events in the SPIN trial
| Event category/episode . | Pharmacologic intervention group, n . | Intensive surveillance group, n . |
|---|---|---|
| Serious adverse event | ||
| Antepartum hemorrhage/vaginal bleed | 10 | 10 |
| Postpartum hemorrhage | 14 | 13 |
| Low hemoglobin | 0 | 1 |
| Nonserious adverse event | ||
| Antepartum hemorrhage/vaginal bleed | 45 | 31 |
| Injection site/abdominal bruising | 16 | 0 |
| Nosebleed | 13 | 0 |
| Bleeding (other) | 6 | 0 |
| Postpartum hemorrhage | 3 | 5 |
| Anemia | 3 | 1 |
| Injection site pain | 1 | 0 |
| Injection site itch | 2 | 0 |
| Injection site or other rash | 2 | 0 |
| Gastric upset | 2 | 0 |
| Low platelet count | 0 | 1 |
| Event category/episode . | Pharmacologic intervention group, n . | Intensive surveillance group, n . |
|---|---|---|
| Serious adverse event | ||
| Antepartum hemorrhage/vaginal bleed | 10 | 10 |
| Postpartum hemorrhage | 14 | 13 |
| Low hemoglobin | 0 | 1 |
| Nonserious adverse event | ||
| Antepartum hemorrhage/vaginal bleed | 45 | 31 |
| Injection site/abdominal bruising | 16 | 0 |
| Nosebleed | 13 | 0 |
| Bleeding (other) | 6 | 0 |
| Postpartum hemorrhage | 3 | 5 |
| Anemia | 3 | 1 |
| Injection site pain | 1 | 0 |
| Injection site itch | 2 | 0 |
| Injection site or other rash | 2 | 0 |
| Gastric upset | 2 | 0 |
| Low platelet count | 0 | 1 |
No serious adverse reactions were reported.