Table 7

Recommended evaluations for children newly diagnosed with ITP and no improvement after 3 to 6 months

  • Bone marrow evaluation (recommended if ITP persists and no prior response)

  • Tests to identify infection (HIV/HCV/H pylori) if clinical suspicion or high local prevalence

  • ANA

  • Testing for APLA including ACA and LAC

  • Serum immunoglobulins (IgG, IgA, IgM)

  • Review of medication usage

 

  • Bone marrow evaluation (recommended if ITP persists and no prior response)

  • Tests to identify infection (HIV/HCV/H pylori) if clinical suspicion or high local prevalence

  • ANA

  • Testing for APLA including ACA and LAC

  • Serum immunoglobulins (IgG, IgA, IgM)

  • Review of medication usage

 

Refer also to corresponding topics under “Management of adult ITP,” and supplemental Document 6.

ANA indicates antinuclear antibody; APLA, antiphospholipid antibodies; ACA, anticardiolipin antibody; and LAC, lupus anticoagulant.

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