Table 4

In vivo reversion of the genetic mutation introduced in the 30KO and HBZKO viruses in the tissues of the infected macaques

Animal no.Weeks after infectionClones with mutated viral sequence/no. of clones sequenced
p30 KO   
    P064 (BM) 46 0/10 
    P011 (PBMC) 12 0/10 
pHBZ KO   
    P068 (BM) 46 0/10 
    M902 (PBMC) 12 1/6 
    P069 (PBMC) 10/10 
 9/10 
 10 3/10 
 12 1/10 
Animal no.Weeks after infectionClones with mutated viral sequence/no. of clones sequenced
p30 KO   
    P064 (BM) 46 0/10 
    P011 (PBMC) 12 0/10 
pHBZ KO   
    P068 (BM) 46 0/10 
    M902 (PBMC) 12 1/6 
    P069 (PBMC) 10/10 
 9/10 
 10 3/10 
 12 1/10 

BM indicates bone marrow.

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