Multivariate analysis for probability of overall survival in 192 consecutive children with advanced MDS and different karyotypic complexities
| Variable . | Relative risk of death . | 95% CI . | P . |
|---|---|---|---|
| Age at diagnosis ≥ 15 y | 1.7 | 1.0-2.9 | .05 |
| Male sex | 1.2 | 0.8-2.0 | NS |
| Secondary MDS | 1.0 | 0.6-1.8 | NS |
| Different karyotypic complexities | |||
| Monosomal karyotype but not structurally complex (n = 11) | 0.6 | 0.2-1.9 | NS |
| Structurally complex and monosomal karyotype (n = 19) | 4.6 | 2.2-9.5 | < .01 |
| Structurally complex but not monosomal (n = 9) | 14.5 | 5.1-41.2 | < .01 |
| HSCT | 0.4 | 0.2-1.0 | .05 |
| Variable . | Relative risk of death . | 95% CI . | P . |
|---|---|---|---|
| Age at diagnosis ≥ 15 y | 1.7 | 1.0-2.9 | .05 |
| Male sex | 1.2 | 0.8-2.0 | NS |
| Secondary MDS | 1.0 | 0.6-1.8 | NS |
| Different karyotypic complexities | |||
| Monosomal karyotype but not structurally complex (n = 11) | 0.6 | 0.2-1.9 | NS |
| Structurally complex and monosomal karyotype (n = 19) | 4.6 | 2.2-9.5 | < .01 |
| Structurally complex but not monosomal (n = 9) | 14.5 | 5.1-41.2 | < .01 |
| HSCT | 0.4 | 0.2-1.0 | .05 |
CI indicates confidence interval; and NS, not significant.