Biomarkers in follicular lymphoma
| Biomarker . | No. failed . | No. positive (%) . | Morphological pattern . | OS P . | PFS P . | Comments . |
|---|---|---|---|---|---|---|
| CD4+ cells | 2 | 78 (76) | NS | NS | Quantity of T cells (+/++/+++) | |
| CD4/CD8 pattern | 5 | 71 (71) | Follicular | NS | .056 | Preferential intrafollicular CD4 and perifollicular CD8 localization |
| CD25+ cells | 6 | 51 (52) | NS | NS | > 200 cells/core (100X) | |
| CD25 pattern | 6 | 40 (40) | Follicular | .024 | .002 | Preferential intrafollicular or/and perifollicular localization |
| FOXP3+ cells | 3 | 34 (33) | NS | NS | > 300 cells/core (100x) | |
| FOXP3 pattern | 3 | 38 (36) | Follicular | < .001 | .001 | Preferential intrafollicular or/and perifollicular localization |
| Biomarker . | No. failed . | No. positive (%) . | Morphological pattern . | OS P . | PFS P . | Comments . |
|---|---|---|---|---|---|---|
| CD4+ cells | 2 | 78 (76) | NS | NS | Quantity of T cells (+/++/+++) | |
| CD4/CD8 pattern | 5 | 71 (71) | Follicular | NS | .056 | Preferential intrafollicular CD4 and perifollicular CD8 localization |
| CD25+ cells | 6 | 51 (52) | NS | NS | > 200 cells/core (100X) | |
| CD25 pattern | 6 | 40 (40) | Follicular | .024 | .002 | Preferential intrafollicular or/and perifollicular localization |
| FOXP3+ cells | 3 | 34 (33) | NS | NS | > 300 cells/core (100x) | |
| FOXP3 pattern | 3 | 38 (36) | Follicular | < .001 | .001 | Preferential intrafollicular or/and perifollicular localization |
OS indicates overall survival; PFS, progression-free survival; and NS, not significant.