Baseline patient characteristics
| Characteristic . | All subjects (n = 419) . | FC arm (n = 209) . | R-FC arm (n = 210) . | P . |
|---|---|---|---|---|
| Median age, y (range) | 63 (35-83) | 61 (37-81) | 63 (35-83) | .75 |
| Sex | .18 | |||
| Female | 139 (33%) | 76 (36%) | 63 (30%) | |
| Male | 280 (67%) | 133 (64%) | 147 (70%) | |
| Binet stage | .83 | |||
| A | 40 (10%) | 21 (10%) | 19 (9%) | |
| B | 247 (59%) | 120 (57%) | 127 (61%) | |
| C | 132 (31%) | 68 (33%) | 64 (30%) | |
| Del(17p) | 35/415 (8%) | 20/206 (10%) | 15/209 (7%) | .38 |
| Del(11q) | 86/416 (21%) | 47/206 (23%) | 39/210 (19%) | .33 |
| IgVH status, n | 410 | 208 | 202 | .54 |
| Mutated | 154 (38%) | 75 (36%) | 79 (39%) | |
| Unmutated | 256 (62%) | 133 (64%) | 123 (61%) | |
| ZAP70 expression, n | 368 | 179 | 189 | .92 |
| Negative | 166 (45%) | 80 (46%) | 86 (46%) | |
| Positive | 202 (55%) | 99 (54%) | 103 (54%) | |
| CD38 expression, n | 267 | 133 | 134 | .39 |
| Negative | 135 (51%) | 71 (53%) | 64 (48%) | |
| Positive | 132 (49%) | 62 (47%) | 70 (52%) |
| Characteristic . | All subjects (n = 419) . | FC arm (n = 209) . | R-FC arm (n = 210) . | P . |
|---|---|---|---|---|
| Median age, y (range) | 63 (35-83) | 61 (37-81) | 63 (35-83) | .75 |
| Sex | .18 | |||
| Female | 139 (33%) | 76 (36%) | 63 (30%) | |
| Male | 280 (67%) | 133 (64%) | 147 (70%) | |
| Binet stage | .83 | |||
| A | 40 (10%) | 21 (10%) | 19 (9%) | |
| B | 247 (59%) | 120 (57%) | 127 (61%) | |
| C | 132 (31%) | 68 (33%) | 64 (30%) | |
| Del(17p) | 35/415 (8%) | 20/206 (10%) | 15/209 (7%) | .38 |
| Del(11q) | 86/416 (21%) | 47/206 (23%) | 39/210 (19%) | .33 |
| IgVH status, n | 410 | 208 | 202 | .54 |
| Mutated | 154 (38%) | 75 (36%) | 79 (39%) | |
| Unmutated | 256 (62%) | 133 (64%) | 123 (61%) | |
| ZAP70 expression, n | 368 | 179 | 189 | .92 |
| Negative | 166 (45%) | 80 (46%) | 86 (46%) | |
| Positive | 202 (55%) | 99 (54%) | 103 (54%) | |
| CD38 expression, n | 267 | 133 | 134 | .39 |
| Negative | 135 (51%) | 71 (53%) | 64 (48%) | |
| Positive | 132 (49%) | 62 (47%) | 70 (52%) |