Multivariate analysis of prognostic factors for CR and OS
| Characteristic . | Estimated HR for CR . | P . | Estimated HR for OS . | P . |
|---|---|---|---|---|
| Platelet, ×109/L | ||||
| < 30 | 0.25 | .006 | 1.76 | .001 |
| Cytogenetic | ||||
| Unfavorable | 0.18 | .002 | 1.95 | < .001 |
| WBC, ×109/L | ||||
| ≥ 10.0 | ns | 2.14 | .007 | |
| Marrow blast, % | ||||
| Increased | ns | 1.01 | < .001 | |
| AHD | ||||
| Yes | 0.33 | .02 | ns | |
| Salvage Rx | ||||
| Non-AlloSCT | 0.06 | < .001 | ns |
| Characteristic . | Estimated HR for CR . | P . | Estimated HR for OS . | P . |
|---|---|---|---|---|
| Platelet, ×109/L | ||||
| < 30 | 0.25 | .006 | 1.76 | .001 |
| Cytogenetic | ||||
| Unfavorable | 0.18 | .002 | 1.95 | < .001 |
| WBC, ×109/L | ||||
| ≥ 10.0 | ns | 2.14 | .007 | |
| Marrow blast, % | ||||
| Increased | ns | 1.01 | < .001 | |
| AHD | ||||
| Yes | 0.33 | .02 | ns | |
| Salvage Rx | ||||
| Non-AlloSCT | 0.06 | < .001 | ns |
CR indicates complete response; AlloSCT, allogeneic stem cell transplantation; AHD, antecedent hematologic disorder; HR, hazard ratio; ns, not significant; OS, overall survival; WBC, white blood cells; and Rx, treatment.