Best response to treatment for the treated population and the phase 2 population
| Response* . | All patients (N = 66) . | Phase 2 population (n = 35) . | ||||
|---|---|---|---|---|---|---|
| n . | % . | 90% CI . | n . | % . | 90% CI . | |
| CR | 19 | 29 | 20-39 | 13 | 37 | 24-52 |
| nCR | 7 | 11 | 5-19 | 7 | 20 | 10-34 |
| VGPR | 18 | 27 | 18-38 | 6 | 17 | 8-31 |
| PR | 22 | 33 | 24-44 | 9 | 26 | 14-41 |
| CR + nCR | 26 | 39 | 29-50 | 20 | 57 | 42-71 |
| CR + nCR + VGPR | 44 | 67 | 56-76 | 26 | 74 | 59-86 |
| At least PR | 66 | 100 | 96-100 | 35 | 100 | 92-100 |
| Response* . | All patients (N = 66) . | Phase 2 population (n = 35) . | ||||
|---|---|---|---|---|---|---|
| n . | % . | 90% CI . | n . | % . | 90% CI . | |
| CR | 19 | 29 | 20-39 | 13 | 37 | 24-52 |
| nCR | 7 | 11 | 5-19 | 7 | 20 | 10-34 |
| VGPR | 18 | 27 | 18-38 | 6 | 17 | 8-31 |
| PR | 22 | 33 | 24-44 | 9 | 26 | 14-41 |
| CR + nCR | 26 | 39 | 29-50 | 20 | 57 | 42-71 |
| CR + nCR + VGPR | 44 | 67 | 56-76 | 26 | 74 | 59-86 |
| At least PR | 66 | 100 | 96-100 | 35 | 100 | 92-100 |
CI indicates confidence interval; CR, complete response; nCR, near-complete response; PR, partial response; VGPR, very good partial response.
Per EBMT criteria,23 all response categories, including VGPR, required a confirmatory assessment at 6 weeks.