Functional Annotation Clustering of differentially expressed genes
| Annotation term . | P . | False discovery rate . |
|---|---|---|
| Annotation cluster 1 Enrichment score: 9.08 | ||
| Cell activation | 3.3 × 10−13 | 6.0 × 10−10 |
| Leukocyte activation | 8.6 × 10−13 | 1.5 × 10−9 |
| Lymphocyte activation | 1.1 × 10−11 | 2.0 × 10−8 |
| Lymphocyte differentiation | 2.3 × 10−11 | 4.1 × 10−8 |
| Leukocyte differentiation | 3.8 × 10−11 | 6.9 × 10−8 |
| Hematopoietic or lymphoid organ development | 1.4 × 10−10 | 2.6 × 10−7 |
| Immune system development | 9.0 × 10−10 | 1.6 × 10−6 |
| Hemopoiesis | 1.6 × 9−13 | 2.8 × 10−6 |
| T-cell activation | 1.1 × 10−8 | 2.0 × 10−5 |
| T-cell differentiation | 1.1 × 10−8 | 2.0 × 10−5 |
| B-cell activation | 1.9 × 10−5 | 3.4 × 10−2 |
| B-cell differentiation | 9.9 × 10−5 | 1.8 × 10−1 |
| Annotation cluster 2 Enrichment score: 8.09 | ||
| Immunoglobulin-like | 2.5 × 10−15 | 3.9 × 10−12 |
| Immunoglobulin-like fold | 3.0 × 10−15 | 4.8 × 10−12 |
| Immunoglobulin domain | 5.6 × 10−11 | 8.1 × 10−8 |
| Immunoglobulin V-set | 2.1 × 10−4 | 3.4 × 10−1 |
| Immunoglobulin subtype | 3.0 × 10−4 | 4.8 × 10−1 |
| Immunoglobulin | 1.1 × 10−2 | 1.3 × 10 |
| Annotation term . | P . | False discovery rate . |
|---|---|---|
| Annotation cluster 1 Enrichment score: 9.08 | ||
| Cell activation | 3.3 × 10−13 | 6.0 × 10−10 |
| Leukocyte activation | 8.6 × 10−13 | 1.5 × 10−9 |
| Lymphocyte activation | 1.1 × 10−11 | 2.0 × 10−8 |
| Lymphocyte differentiation | 2.3 × 10−11 | 4.1 × 10−8 |
| Leukocyte differentiation | 3.8 × 10−11 | 6.9 × 10−8 |
| Hematopoietic or lymphoid organ development | 1.4 × 10−10 | 2.6 × 10−7 |
| Immune system development | 9.0 × 10−10 | 1.6 × 10−6 |
| Hemopoiesis | 1.6 × 9−13 | 2.8 × 10−6 |
| T-cell activation | 1.1 × 10−8 | 2.0 × 10−5 |
| T-cell differentiation | 1.1 × 10−8 | 2.0 × 10−5 |
| B-cell activation | 1.9 × 10−5 | 3.4 × 10−2 |
| B-cell differentiation | 9.9 × 10−5 | 1.8 × 10−1 |
| Annotation cluster 2 Enrichment score: 8.09 | ||
| Immunoglobulin-like | 2.5 × 10−15 | 3.9 × 10−12 |
| Immunoglobulin-like fold | 3.0 × 10−15 | 4.8 × 10−12 |
| Immunoglobulin domain | 5.6 × 10−11 | 8.1 × 10−8 |
| Immunoglobulin V-set | 2.1 × 10−4 | 3.4 × 10−1 |
| Immunoglobulin subtype | 3.0 × 10−4 | 4.8 × 10−1 |
| Immunoglobulin | 1.1 × 10−2 | 1.3 × 10 |
The list of differentially expressed genes was used as input for the Functional Annotation Clustering function of DAVID Bioinformatics Resources 6.7.29 The 2 most relevant clusters are reported.