Table 3

Top 20 most strongly down-regulated transcripts detected by microarray analysis

Fold difference HOXB4/GFPGenBankGene symbolGene title
−308.55* NM_008219 Hbb-bh1 Hemoglobin Z, β-like embryonic chain 
−157.31* NM_133245 Eraf Erythroid-associated factor 
−78.37* NM_011269 Rhag Rhesus blood group-associated A glycoprotein 
−76.22* NM_013848 Ermap Erythroblast membrane–associated protein 
−55.11 NM_020504 Cldn13 Claudin 13 
−44.45 D85596 Ampd3 AMP deaminase 3 
−36.28 BC027185 2210023G05Rik RIKEN cDNA 2210023G05 gene 
−35.31* NM_010369 Gypa Glycophorin A 
−29.88* NM_010635 Klf1 Kruppel-like factor 1 (erythroid) 
−29.77* NM_008218 Hba-a1 Hemoglobin α, adult chain 1 
−26.57* BC011223 Car1 Carbonic anhydrase 1 
−25.79 BB729271 — Transcribed locus 
−23.46 AK007743 Pdia2 Protein disulfide isomerase associated 2 
−22.27* AF069311 Rhd Rh blood group, D antigen 
−20.86 NM_008560 Mc2r Melanocortin 2 receptor 
−20.81* AV156860 Hbb-y Hemoglobin Y, β-like embryonic chain 
−19.85* NM_032540 Kel Kell blood group 
−19.50 AV048291 C1qdc2 C1q domain containing 2 
−17.30 NM_011452 Serpinb9b Serine (or cysteine) peptidase inhibitor, clade B, member 9b 
−13.80* BB740660 LOC630963 Similar to spectrin α 1 
Fold difference HOXB4/GFPGenBankGene symbolGene title
−308.55* NM_008219 Hbb-bh1 Hemoglobin Z, β-like embryonic chain 
−157.31* NM_133245 Eraf Erythroid-associated factor 
−78.37* NM_011269 Rhag Rhesus blood group-associated A glycoprotein 
−76.22* NM_013848 Ermap Erythroblast membrane–associated protein 
−55.11 NM_020504 Cldn13 Claudin 13 
−44.45 D85596 Ampd3 AMP deaminase 3 
−36.28 BC027185 2210023G05Rik RIKEN cDNA 2210023G05 gene 
−35.31* NM_010369 Gypa Glycophorin A 
−29.88* NM_010635 Klf1 Kruppel-like factor 1 (erythroid) 
−29.77* NM_008218 Hba-a1 Hemoglobin α, adult chain 1 
−26.57* BC011223 Car1 Carbonic anhydrase 1 
−25.79 BB729271 — Transcribed locus 
−23.46 AK007743 Pdia2 Protein disulfide isomerase associated 2 
−22.27* AF069311 Rhd Rh blood group, D antigen 
−20.86 NM_008560 Mc2r Melanocortin 2 receptor 
−20.81* AV156860 Hbb-y Hemoglobin Y, β-like embryonic chain 
−19.85* NM_032540 Kel Kell blood group 
−19.50 AV048291 C1qdc2 C1q domain containing 2 
−17.30 NM_011452 Serpinb9b Serine (or cysteine) peptidase inhibitor, clade B, member 9b 
−13.80* BB740660 LOC630963 Similar to spectrin α 1 
*

Gene transcripts that are erythroid-specific and represent more than half of the top 20 most strongly down-regulated transcripts.

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