Table 1

Cuticular bleeding time

GenotypeNo. of animals studiedClotting time, hOriginal hemoglobin, %
WT 0.7 ± 0.7 71 ± 15 
F8null > 6 25 ± 6 
phF8.38/F8null 2.6 ± 1.2 65 ± 20 
pIR8.5/F8null 1.6 ± 0.1 70 ± 14 
pIR8.16/F8null 3.5 ± 0.3 69 ± 14 
pIR8.18/F8null 2.6 ± 0.1 67 ± 23 
pcF8.24/F8null 1.1 ± 0.3 66 ± 19 
pcF8.45/F8null 1.2 ± 0.3 79 ± 14 
GenotypeNo. of animals studiedClotting time, hOriginal hemoglobin, %
WT 0.7 ± 0.7 71 ± 15 
F8null > 6 25 ± 6 
phF8.38/F8null 2.6 ± 1.2 65 ± 20 
pIR8.5/F8null 1.6 ± 0.1 70 ± 14 
pIR8.16/F8null 3.5 ± 0.3 69 ± 14 
pIR8.18/F8null 2.6 ± 0.1 67 ± 23 
pcF8.24/F8null 1.1 ± 0.3 66 ± 19 
pcF8.45/F8null 1.2 ± 0.3 79 ± 14 

Clotting time in hours and the percentage of original hemoglobin at the end of the 6-hour study. Values are shown as means ± 1 SD.

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