Characteristics of the candidate gene SNPs
| Gene . | Gene description . | SNP ID . | Alleles A/B* (freq) . | Chromosome . | Sequence position† . | Codon change . | aa change . | Taqman assay ID . |
|---|---|---|---|---|---|---|---|---|
| ERCC2 (XPD) | Excision repair cross-complementing rodent repair deficiency, complementation group 2 | rs13181 | A/C (0.36) | 19 | exon 23 (751) | AAG/CAG | Lys/Gln | C_3145033_10 |
| ERCC5 (XPG) | ERCC5 excision repair cross-complementing rodent repair deficiency, complementation group 5 | rs17655 | G/C (0.28) | 13 | exon 4 (1104) | GAT/CAT | Asp/His | C_1891743_10 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 | rs25487 | G/A (0.38) | 19 | exon 10 (399) | CGG/CAG | Arg/Gln | C_622564_10 |
| XPC | XPC xeroderma pigmentosum, complementation group C | rs2228000 | C/T (0.29) | 3 | exon 8 (499) | GCG/GTG | Ala/Val | C_16018061_10 |
| rs2228001 | A/C (0.40) | 3 | exon 16 (939) | AAG/CAG | Lys/Gln | C_234284_1 |
| Gene . | Gene description . | SNP ID . | Alleles A/B* (freq) . | Chromosome . | Sequence position† . | Codon change . | aa change . | Taqman assay ID . |
|---|---|---|---|---|---|---|---|---|
| ERCC2 (XPD) | Excision repair cross-complementing rodent repair deficiency, complementation group 2 | rs13181 | A/C (0.36) | 19 | exon 23 (751) | AAG/CAG | Lys/Gln | C_3145033_10 |
| ERCC5 (XPG) | ERCC5 excision repair cross-complementing rodent repair deficiency, complementation group 5 | rs17655 | G/C (0.28) | 13 | exon 4 (1104) | GAT/CAT | Asp/His | C_1891743_10 |
| XRCC1 | X-ray repair complementing defective repair in Chinese hamster cells 1 | rs25487 | G/A (0.38) | 19 | exon 10 (399) | CGG/CAG | Arg/Gln | C_622564_10 |
| XPC | XPC xeroderma pigmentosum, complementation group C | rs2228000 | C/T (0.29) | 3 | exon 8 (499) | GCG/GTG | Ala/Val | C_16018061_10 |
| rs2228001 | A/C (0.40) | 3 | exon 16 (939) | AAG/CAG | Lys/Gln | C_234284_1 |