Table 2

Factors to predict unfavorable prognostic features for DFS and OS by multivariate analysis

Survival type/variableCategoryHazard ratioP
DFS    
    Initial WBC count ≥ 20 × 109/L 1.49 < .0001 
    No. of induction therapies 2 courses 1.50 .0006 
    Age, y > 50 1.33 .0028 
    Consolidation therapy Multiagent CT 1.04 .7128 
OS    
    Age, y > 50 2.00 < .0001 
    No. of induction therapies 2 courses 1.58 .0033 
    Initial WBC count ≥ 20 × 109/L 1.41 .0070 
    MPO-positive blast < 50 % 1.42 .0149 
    Consolidation therapy Multiagent CT 0.96 .7768 
Survival type/variableCategoryHazard ratioP
DFS    
    Initial WBC count ≥ 20 × 109/L 1.49 < .0001 
    No. of induction therapies 2 courses 1.50 .0006 
    Age, y > 50 1.33 .0028 
    Consolidation therapy Multiagent CT 1.04 .7128 
OS    
    Age, y > 50 2.00 < .0001 
    No. of induction therapies 2 courses 1.58 .0033 
    Initial WBC count ≥ 20 × 109/L 1.41 .0070 
    MPO-positive blast < 50 % 1.42 .0149 
    Consolidation therapy Multiagent CT 0.96 .7768 

MPO indicates myeloperoxidase.

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