Neutrophilia is prolonged and exaggerated in CGD
| Mouse* . | ψmax, ×106 . | Tmax, h . | T50, h . | Ri, h . | Ipmn=mono, h . |
|---|---|---|---|---|---|
| WT | 22.8 ± 1.3 | 16 ± 3.5 | 29 ± 2.1 | 13.0 ± 1.6 | 31.4 ± 1.5 |
| CGD | 32.5 ± 5.5* | 18.8 ± 1.1 | 58.3 ± 1.4* | 39.5 ± 0.5* | 78.3 ± 1.4* |
| Mouse* . | ψmax, ×106 . | Tmax, h . | T50, h . | Ri, h . | Ipmn=mono, h . |
|---|---|---|---|---|---|
| WT | 22.8 ± 1.3 | 16 ± 3.5 | 29 ± 2.1 | 13.0 ± 1.6 | 31.4 ± 1.5 |
| CGD | 32.5 ± 5.5* | 18.8 ± 1.1 | 58.3 ± 1.4* | 39.5 ± 0.5* | 78.3 ± 1.4* |
Data from Figures 1A and 3A were analyzed for ψmax (maximal numbers of neutrophils recovered), Tmax (time to ψmax), T50 (time when neutrophil numbers reach half maximum), Ri (Tmax − T50) and Ipmn = mono (time when there are equal numbers of macrophages and neutrophils) as previously described (Bannenberg et al35 ).
P ≤ .04 compared to WT.