Table 2 Distribution of 3-week platelet... | American Society of Hematology

Table 2

Distribution of 3-week platelet and neutrophil-producing activities between Lin⁻ALDH⁺CD38⁺ and Lin⁻ALDH⁺CD38⁻ cells in CB

End point	CB pool no. 1				CB pool no. 2
	CD38⁺		CD38⁻		CD38⁺		CD38⁻
	Total	%	Total	%	Total	%	Total	%
Human platelets, (×10³)/mL mouse PB*	260 ± 100	41	370 ± 77	59	210 ± 100	37	360 ± 150	63
Primitive CFU-Mks, > 50 Mks/colony†	6300	55	5200	45	550	58	400	42
Mature CFU-Mks, 3-49 Mks/colony†	13 000	53	11 000	47	7300	53	6600	47
Human neutrophils in mouse BM, %*	ND	—	ND	—	12 ± 8	85	2 ± 1	15
Primitive CFU-GMs, > 1000 cells/colony†	26 000	55	21 000	45	9200	38	15 000	62
Mature CFU-GMs, 20-1000 cells/colony†	23 000	56	18 000	44	9100	63	5400	37

End point	CB pool no. 1				CB pool no. 2
	CD38⁺		CD38⁻		CD38⁺		CD38⁻
	Total	%	Total	%	Total	%	Total	%
Human platelets, (×10³)/mL mouse PB*	260 ± 100	41	370 ± 77	59	210 ± 100	37	360 ± 150	63
Primitive CFU-Mks, > 50 Mks/colony†	6300	55	5200	45	550	58	400	42
Mature CFU-Mks, 3-49 Mks/colony†	13 000	53	11 000	47	7300	53	6600	47
Human neutrophils in mouse BM, %*	ND	—	ND	—	12 ± 8	85	2 ± 1	15
Primitive CFU-GMs, > 1000 cells/colony†	26 000	55	21 000	45	9200	38	15 000	62
Mature CFU-GMs, 20-1000 cells/colony†	23 000	56	18 000	44	9100	63	5400	37

In vivo data shown are the means ± SEM of results from 3 mice per group (Lin⁻ALDH⁺CD38⁺ and Lin⁻ALDH⁺CD38⁻ cells) in each experiment.

ND indicates not detectable; and —, not applicable. See Table 1 for expansion of other abbreviations.

Per 2.5 × 10⁴ Lin⁻ human cells.

Per 10⁵ Lin⁻ human cells.