Univariate and multivariate analysis for OS in MDS patients
| . | OS univariate analysis . | OS multivariate analysis . | ||||
|---|---|---|---|---|---|---|
| HR* . | 95% CI . | P . | HR* . | 95% CI . | P . | |
| SRSF2 mutation status, mutated vs WT | 1.76 | 1.0-3.1 | .049 | 2.3 | 1.28-4.13 | .017 |
| ASXL1 mutation status, mutated vs WT | 2.06 | 1.21-3.50 | .008 | 2.01 | 1.13-3.57 | .017 |
| RUNX1 mutation status, mutated vs WT | 2.44 | 1.21-4.92 | .013 | 1.28 | 0.60-2.71 | .53 |
| IDH1 mutation status, mutated vs WT | 3.28 | 1.48-7.05 | .003 | 1.90 | 0.79-4.58 | .16 |
| NRAS mutation status, mutated vs WT | 5.39 | 2.29-12.66 | < .001 | 5.25 | 1.99-13.84 | .001 |
| Transfusion dependence, dependent vs independent | 3.72 | 1.70-8.14 | .001 | 2.79 | 1.23-6.36 | .014 |
| IPSS, low vs intermediate 1 vs intermediate 2 vs high | 1.73 | 1.35-2.2 | < .001 | 1.48 | 1.13-1.94 | .005 |
| . | OS univariate analysis . | OS multivariate analysis . | ||||
|---|---|---|---|---|---|---|
| HR* . | 95% CI . | P . | HR* . | 95% CI . | P . | |
| SRSF2 mutation status, mutated vs WT | 1.76 | 1.0-3.1 | .049 | 2.3 | 1.28-4.13 | .017 |
| ASXL1 mutation status, mutated vs WT | 2.06 | 1.21-3.50 | .008 | 2.01 | 1.13-3.57 | .017 |
| RUNX1 mutation status, mutated vs WT | 2.44 | 1.21-4.92 | .013 | 1.28 | 0.60-2.71 | .53 |
| IDH1 mutation status, mutated vs WT | 3.28 | 1.48-7.05 | .003 | 1.90 | 0.79-4.58 | .16 |
| NRAS mutation status, mutated vs WT | 5.39 | 2.29-12.66 | < .001 | 5.25 | 1.99-13.84 | .001 |
| Transfusion dependence, dependent vs independent | 3.72 | 1.70-8.14 | .001 | 2.79 | 1.23-6.36 | .014 |
| IPSS, low vs intermediate 1 vs intermediate 2 vs high | 1.73 | 1.35-2.2 | < .001 | 1.48 | 1.13-1.94 | .005 |
HR > 1 indicates an increased risk of an event for the first category listed.