Significance data for gene set enrichment analysis comparisons between wild-type and BR cells for the myeloma lines studied using sets of IGF-1–regulated genes in MCF-7 breast carcinoma27
| Gene set . | Total no. of genes . | ES . | NES . | Nominal P value . | FDR q value . |
|---|---|---|---|---|---|
| Up in MCF-7 with IGF-1 | 377 | ||||
| OPM2* | 0.45 | 1.94 | .000 | .071 | |
| 8226 | 0.36 | 1.57 | .000 | .079 | |
| ANBL-6 | 0.38 | 1.59 | .000 | .214 | |
| Down in MCF-7 with IGF-1 | 374 | ||||
| OPM2* | −0.45 | −1.89 | .000 | .010 | |
| 8226 | −0.45 | −1.85 | .000 | .017 | |
| ANBL-6 | −0.37 | −1.51 | .000 | .206 |
| Gene set . | Total no. of genes . | ES . | NES . | Nominal P value . | FDR q value . |
|---|---|---|---|---|---|
| Up in MCF-7 with IGF-1 | 377 | ||||
| OPM2* | 0.45 | 1.94 | .000 | .071 | |
| 8226 | 0.36 | 1.57 | .000 | .079 | |
| ANBL-6 | 0.38 | 1.59 | .000 | .214 | |
| Down in MCF-7 with IGF-1 | 374 | ||||
| OPM2* | −0.45 | −1.89 | .000 | .010 | |
| 8226 | −0.45 | −1.85 | .000 | .017 | |
| ANBL-6 | −0.37 | −1.51 | .000 | .206 |
ES indicates enrichment score; NES, normalized enrichment score; and FDR, false discovery rate.
OPM2 was studied twice.