Table 5 Results of SNP genotyping on... | American Society of Hematology

Table 5

Results of SNP genotyping on HLA-matched recipient samples

Gene	Marker	Discovery cohort (genotype and association)	Confirmatory cohort (genotype and association)
FAS	rs1800682	CT aGVHD* (P = .0024, OR = 0.39,* CI = 0.22-0.71)	NS
IL1B	rs16944	AA aGVHD (P = .043, OR = 0.51, CI = 0.27-0.97)	NT
IL2	rs2069762	GT survival (P = .037) protective	NS
		GT cGVHD (P = .039, OR = 1.97, CI = 1.05-3.71)	GT cGVHD† (P = .00041,† OR = 3.24,*† CI = 1.69-6.20)
		TT survival (P = .039) risk	NS

Gene	Marker	Discovery cohort (genotype and association)	Confirmatory cohort (genotype and association)
FAS	rs1800682	CT aGVHD* (P = .0024, OR = 0.39,* CI = 0.22-0.71)	NS
IL1B	rs16944	AA aGVHD (P = .043, OR = 0.51, CI = 0.27-0.97)	NT
IL2	rs2069762	GT survival (P = .037) protective	NS
		GT cGVHD (P = .039, OR = 1.97, CI = 1.05-3.71)	GT cGVHD† (P = .00041,† OR = 3.24,*† CI = 1.69-6.20)
		TT survival (P = .039) risk	NS

NS indicates not significant; and NT, not tested.

Withstanding Bonferroni multiple testing corrections or have OR ≤ 0.5 or ≥ 2.

Consistent associations.